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Development and Validation of a Novel Generic Health-related Quality of Life Instrument With 20 Items (HINT-20)
Min-Woo Jo, Hyeon-Jeong Lee, Soo Young Kim, Seon-Ha Kim, Hyejung Chang, Jeonghoon Ahn, Minsu Ock
J Prev Med Public Health. 2017;50(1):38-59.   Published online January 10, 2017
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  • 215 Download
  • 6 Crossref
AbstractAbstract PDFSupplementary Material
Few attempts have been made to develop a generic health-related quality of life (HRQoL) instrument and to examine its validity and reliability in Korea. We aimed to do this in our present study.
After a literature review of existing generic HRQoL instruments, a focus group discussion, in-depth interviews, and expert consultations, we selected 30 tentative items for a new HRQoL measure. These items were evaluated by assessing their ceiling effects, difficulty, and redundancy in the first survey. To validate the HRQoL instrument that was developed, known-groups validity and convergent/discriminant validity were evaluated and its test-retest reliability was examined in the second survey.
Of the 30 items originally assessed for the HRQoL instrument, four were excluded due to high ceiling effects and six were removed due to redundancy. We ultimately developed a HRQoL instrument with a reduced number of 20 items, known as the Health-related Quality of Life Instrument with 20 items (HINT-20), incorporating physical, mental, social, and positive health dimensions. The results of the HINT-20 for known-groups validity were poorer in women, the elderly, and those with a low income. For convergent/discriminant validity, the correlation coefficients of items (except vitality) in the physical health dimension with the physical component summary of the Short Form 36 version 2 (SF-36v2) were generally higher than the correlations of those items with the mental component summary of the SF-36v2, and vice versa. Regarding test-retest reliability, the intraclass correlation coefficient of the total HINT-20 score was 0.813 (p<0.001).
A novel generic HRQoL instrument, the HINT-20, was developed for the Korean general population and showed acceptable validity and reliability.


Citations to this article as recorded by  
  • A Review of the Types and Characteristics of Healthy Life Expectancy and Methodological Issues
    Young-Eun Kim, Yoon-Sun Jung, Minsu Ock, Seok-Jun Yoon
    Journal of Preventive Medicine and Public Health.2022; 55(1): 1.     CrossRef
  • Health-Related Quality of Life (HRQOL) Instruments and Mobility: A Systematic Review
    Natalia Hernández-Segura, Alba Marcos-Delgado, Arrate Pinto-Carral, Tania Fernández-Villa, Antonio J. Molina
    International Journal of Environmental Research and Public Health.2022; 19(24): 16493.     CrossRef
  • Concepts of Health-Related Quality of Life of Australian Aboriginal and Torres Strait Islander Children: Parent Perceptions
    Kaley Butten, Peter A. Newcombe, Anne B. Chang, Jeanie K. Sheffield, Kerry-Ann F. O’Grady, Newell W. Johnson, Neil King, Maree Toombs
    Applied Research in Quality of Life.2021; 16(4): 1653.     CrossRef
  • Meaning and Status of Health-related Quality of Life Recognized by Medical Professionals: a Qualitative Study
    Jeehee Pyo, Minsu Ock, Bohyun Park, Nam-eun Kim, Eun Jeong Choi, Hyesook Park, Hyeong Sik Ahn
    Journal of Korean Medical Science.2021;[Epub]     CrossRef
  • Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
    Juyoung Kim, Min-Woo Jo, Hyeon-Jeong Lee, Sei-Hyun Ahn, Byung Ho Son, Jong Won Lee, Sae Byul Lee
    Osong Public Health and Research Perspectives.2021; 12(4): 254.     CrossRef
  • Developing a comprehensive, culturally sensitive conceptual framework of health domains in Singapore
    Julian Thumboo, Mandy Y. L. Ow, Elenore Judy B. Uy, Xiaohui Xin, Zi Ying Clarice Chan, Sharon C. Sung, Dianne Carrol Bautista, Yin Bun Cheung, Xiang Li
    PLOS ONE.2018; 13(6): e0199881.     CrossRef
Study on the Exposure Levels of Organic Solvents and Subjective Symptoms of Dry-cleaning Workers.
Soo Young Kim, Jeong Yun Kim, Yeon Kyeng Lee, Sok Goo Lee, Young Soo Lee, Young Chae Cho, Tae Young Lee, Dong Bae Lee
Korean J Prev Med. 1998;31(4):628-643.
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  • 30 Download
AbstractAbstract PDF
To investigate the exposure levels of organic solvents and subjective symptoms of dry-cleaning workers, 77 male and 52 female dry-cleaning workers who had been worked in a small city of Chungnam province, and a large city, Taejon were selected for the study group. Air concentrations of organic solvents in the working environment were analyzed, and subjective symptoms of dry-cleaning workers were surveyed, from July to August 1996. The results obtained were as follows: 1. The concentrations of organic solvents in the working environment were within permissible TLV-TWA limits. 2. For the 13 symptom clusters, the most frequently complained symptom clusters were fatigue as 71.3%, and followed by depression and urinary disturbances as 53.5% and 51.9%. Other symptom clusters complained were below 50%. 3. Positive response rates of subjective symptoms were significantly higher in worker groups such as lived in a large city, female, higher education level, more frequently alcohol drinking, higher concentration of organic solvent in working environment, work in alone. 4. Workers who had used solvent B showed 2.3 point higher scores of subjective symptoms than those of solvent A. Of the subjective symptoms scores, amnesia and nervousness were higher in solvent B user group than solvent B user group. 5. As a result of factor analysis, 3 factors such as depression, urinary disturbance and neurologic disturbance were selected. 6. As a result of the logistic regression analysis, sex, the number of fellow workers, working time, region, job tenure, smoking, alcohol drinking, ventilating system, concentration of organic solvent in working environment and place of residence were selected for the related variables For the conclusion, even though the concentrations of organic solvents in the working environments of dry-cleaning workers were within permissible limit of TLV-TWA, many dry-cleaning workers complained symptoms, such as fatigue, depression, urinary disturbances and so on. And the factors affecting to the symptoms of dry-cleaning workers were the number of fellow workers, work hours, region, job tenure, smoking and alcohol drinking.
Study on the Factors Related to the Cognitive Function and Depression Among the Elderly.
Cheol Ho Shin, Soo Young Kim, Young Soo Lee, Young Chae Cho, Tae Yong Lee, Dong Bae Lee
Korean J Prev Med. 1996;29(2):199-214.
  • 2,167 View
  • 24 Download
AbstractAbstract PDF
To investigate the factors which affecting the cognitive function and depression of the 65 or more age group, the authors surveyed for the subjects in the region of Taejon and nearby Taejon area. 729 studied subjects were tested for cognitive function with MMSE and depression with GDS. The main results were followings; In the studied subjects, the rate of normal cognitive function was 56.8%, the rate of mildly impaired was 24.l% and the rate of severe impairment was 19.l%. The cognitive function level was closely related to the depression score. As the age increased, the cognitive function was more impaired. Sexual difference was also existed in the cognitive function level and the depression score. After adjusting the effect of age, the variables such as sex, marital status, education level, past job, instrumental ability of daily living, regular physical exercise, frequencies of going out the house, chest discomfort, visual and auditory disturbance, and dizziness had the significant relationship with cognitive function impairment. Among these variables instrumental ADL, age, visual disturbance, and sex showed statistical significance in the logistic regression model. In the multiple stepwise regression, the variables which had significant relationship to depression score were education level, frequencies of going out house, current job and house work activity, regular physical exercise, instrumental ADL, self-rated health and nutritional status, dizziness, visual disturbance, and chest pain. In conclusion, main characteristics which had close relationship to the cognitive function and depression symptoms in the studied subjects were physical function and self rated health status.

JPMPH : Journal of Preventive Medicine and Public Health