Journal of Preventive Medicine and Public Health

Original Articles

Predictors and Prevalence of Alcohol and Cannabis Co-use Among Filipino Adolescents: Evidence From a School-based Student Health Survey: Yusuff Adebayo Adebisi, Don Eliseo Lucero-Prisno III, Jerico B. Ogaya, Victor C. Cañezo Jr., Roland A. Niez, Florante E. Delos Santos, Melchor M. Magramo, Ann Rosanie Yap-Tan, Francis Ann R. Sy, Omar Kasimieh; J Prev Med Public Health. 2024;57(3):288-297. Published online May 9, 2024; DOI: https://doi.org/10.3961/jpmph.24.052

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Objectives
This study explored the prevalence and predictors of alcohol and cannabis co-use among 9263 Filipino adolescents, using data from the 2019 Global School-based Student Health Survey (GSHS).
Methods
We conducted a cross-sectional secondary analysis of the GSHS, targeting adolescents aged 13-17 years and excluding cases with incomplete data on alcohol and cannabis use. Our analysis employed the bivariate chi-square test of independence and multivariable logistic regression using Stata version 18 to identify significant predictors of co-use, with a p-value threshold set at 0.05.
Results
The weighted prevalence of co-users was 4.2% (95% confidence interval [CI], 3.4 to 5.3). Significant predictors included male sex (adjusted odds ratio [aOR], 4.50; 95% CI, 3.31 to 6.10; p<0.001) and being in a lower academic year, specifically grade 7 (aOR, 4.08; 95% CI, 2.39 to 6.99; p<0.001) and grade 8 (aOR, 2.20; 95% CI, 1.30 to 3.72; p=0.003). Poor sleep quality was also a significant predictor (aOR, 1.77; 95% CI, 1.29 to 2.44; p<0.001), as was a history of attempted suicide (aOR, 5.31; 95% CI, 4.00 to 7.06; p<0.001). Physical inactivity was associated with lower odds of co-use (aOR, 0.45; 95% CI, 0.33 to 0.62; p<0.001). Additionally, non-attendance of physical education classes (aOR, 1.48; 95% CI, 1.06 to 2.05; p=0.021), infrequent unapproved parental checks (aOR, 1.37; 95% CI, 1.04 to 1.80; p=0.024), and lower parental awareness of free-time activities (aOR, 0.63; 95% CI, 0.45 to 0.87; p=0.005) were associated with higher odds of co-use. Factors not significantly linked to co-use included age group, being in grade 9, always feeling lonely, having no close friends, being bullied outside school, and whether a parent or guardian understood the adolescent’s worries.
Conclusions
The findings highlight the critical need for comprehensive interventions in the Philippines, addressing not only physical inactivity and parental monitoring but also focusing on sex, academic grade, participation in physical education classes, sleep quality, and suicide attempt history, to effectively reduce alcohol and cannabis co-use among adolescents.

Summary

Key Message
This cross-sectional study examines the prevalence and key predictors of alcohol and cannabis co-use among 9263 Filipino adolescents using data from the 2019 Global School-based Student Health Survey. Significant predictors of co-use include male sex, lower academic grade, poor sleep quality, history of attempted suicide, physical inactivity, non-attendance in physical education classes, infrequent parental checks, and low parental awareness of adolescents' activities, with a weighted co-use prevalence of 4.2%. The study underscores the need for comprehensive interventions addressing these factors to reduce substance co-use among Filipino adolescents.

Citations

Citations to this article as recorded by

Comparing self-rated health among exclusive e-cigarette users and traditional cigarette smokers: an analysis of the Health Survey for England 2019
Yusuff Adebayo Adebisi, Duaa Abdullah Bafail
Internal and Emergency Medicine.2025; 20(2): 441. CrossRef
Self-rated health differences between exclusive e-cigarette users and exclusive cigarette smokers: evidence from the 2017–2019 Scottish Health Survey
Yusuff Adebayo Adebisi, Don Eliseo Lucero-Prisno, Isaac Olushola Ogunkola
Internal and Emergency Medicine.2025; 20(3): 771. CrossRef
Prevalence, drug education, and other associated factors of current illicit drug use among a nationally representative sample of school-aged adolescents in the Philippines in 2019
Supa Pengpid, Karl Peltzer, Lyndon Esconde Santos, Earl Francis Infante Mallari
Substance Abuse Treatment, Prevention, and Policy.2025;[Epub] CrossRef
Prevalence Rates, Perceptions of Risk, and Motivations for Nonmedical Cannabis Use in Pediatric Pain
Joe Kossowsky, Christine Greco, Bridget A. Nestor, Camila Koike, Nicole Tacugue, Andreas M. Baumer, Elissa R. Weitzman
JAMA Network Open.2025; 8(5): e2512870. CrossRef
Sleep Disturbances Across the Addiction Stages: A Review of Alcohol, Cannabis and their Co-Use
Claudia B. Padula, Ariel Grayson, Sarah Izabel, Lea-Tereza Tenekedjieva, Emma Zhang, Andrea N. Goldstein-Piekarski
Current Addiction Reports.2025;[Epub] CrossRef
Prevalence, demographic, socio-economic, and lifestyle factors associated with cigarette, e-cigarette, and dual use: evidence from the 2017–2021 Scottish Health Survey
Yusuff Adebayo Adebisi, Duaa Abdullah Bafail, Oluwatobi Ebenezer Oni
Internal and Emergency Medicine.2024; 19(8): 2151. CrossRef

Impact of Physical Activity on the Association Between Unhealthy Adolescent Behaviors and Anxiety Among Korean Adolescents: A Cross-sectional Study: Hyo-jung Lee, Jeong Pil Choi, Kunhee Oh, Jin-Young Min, Kyoung-Bok Min; J Prev Med Public Health. 2023;56(6):552-562. Published online November 15, 2023; DOI: https://doi.org/10.3961/jpmph.23.313

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Abstract Summary PDF: Objectives
Adolescents who engage in unhealthy behaviors are particularly vulnerable to anxiety. We hypothesized that participation in physical activity could influence the relationship between anxiety and unhealthy behaviors in adolescents. These behaviors include smoking, alcohol consumption, and unsafe sexual activity.
Methods
This study included 50 301 students from the first year of middle school to the third year of high school, all from Korea. The unhealthy adolescent behaviors examined included current alcohol consumption, current smoking, and unsafe sexual behavior. Anxiety levels were assessed using the Generalized Anxiety Disorder-7 questionnaire (GAD-7).
Results
The participants had a mean age of 15.19 years and an average GAD-7 score of 4.23. No significant differences were observed in GAD-7 score among exercising participants when categorized by smoking status (p=0.835) or unsafe sexual behavior (p=0.489). In contrast, participants in the non-exercise group who engaged in these behaviors demonstrated significantly higher GAD-7 scores (p<0.001 and 0.016, respectively). The only significant interaction was found between unsafe sexual behavior and exercise (p=0.009). Based on logistic regression analysis, within the non-exercise group, significant positive associations were observed between current smoking and anxiety (odds ratio [OR], 1.36; 95% confidence interval [CI], 1.18 to 1.57), as well as between unsafe sexual behavior and anxiety (OR, 1.33; 95% CI, 1.02 to 1.73). However, within the exercise group, no significant association was found between anxiety and either smoking or unsafe sexual behavior. Furthermore, no significant interaction was observed between unhealthy behaviors and exercise.
Conclusions
These findings are insufficient to conclude that physical activity influences the relationship between unhealthy behaviors and anxiety.; Summary

Korean summary
이 연구는 신체활동이 한국 청소년들사이에서 불안과 불건강행태간의 관계에 어떠한 영향을 미치는지 조사하였다. 이 연구에서 신체활동을 하지 않는 청소년에서만 흡연 및 불안전한 성행위와 같은 불건강행태와 불안 간의 유의미한 연관성을 보였음에도 불구하고, 이러한 불건강행태와 운동 간에는 같은 방향의 유의미한 상호작용이 관찰되지 않았다. 따라서 이 연구는 신체 활동이 청소년들의 불건강행태와 불안간의 관계에 직접 미치는 영향에 대해 명확하게 결론을 내릴 수 없었다.

Key Message
Among Korean adolescents, this study found that significant associations between unhealthy behaviors such as smoking and unsafe sex, and anxiety were only observed in adolescents who did not engage in physical activity. Despite this, no significant interaction was observed between these unhealthy behaviors and exercise. Contrary to popular belief, this study concludes that the evidence is insufficient to definitively say that physical activity influences the relationship between adolescent unhealthy behaviors and anxiety.

Factors Related to Regional Variation in the High-risk Drinking Rate in Korea: Using Quantile Regression: Eun Su Kim, Hae-Sung Nam; J Prev Med Public Health. 2021;54(2):145-152. Published online March 16, 2021; DOI: https://doi.org/10.3961/jpmph.20.507

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Abstract Summary PDF Supplementary Material

Objectives
This study aimed to identify regional differences in the high-risk drinking rate among yearly alcohol users in Korea and to identify relevant regional factors for each quintile using quantile regression.
Methods
Data from 227 counties surveyed by the 2017 Korean Community Health Survey (KCHS) were analyzed. The analysis dataset included secondary data extracted from the Korean Statistical Information Service and data from the KCHS. To identify regional factors related to the high-risk drinking rate among yearly alcohol users, quantile regression was conducted by dividing the data into 10%, 30%, 50%, 70%, and 90% quantiles, and multiple linear regression was also performed.
Results
The current smoking rate, perceived stress rate, crude divorce rate, and financial independence rate, as well as one’s social network, were related to the high-risk drinking rate among yearly alcohol users. The quantile regression revealed that the perceived stress rate was related to all quantiles except for the 90% quantile, and the financial independence rate was related to the 50% to 90% quantiles. The crude divorce rate was related to the high-risk drinking rate among yearly alcohol users in all quantiles.
Conclusions
The findings of this study suggest that local health programs for high-risk drinking are needed in areas with high local stress and high crude divorce rates.

Summary

Korean summary
본 연구는 quantile regression을 이용하여 high risk drinking 의 지역간 변이 요인을 파악하였습니다. 연구결과, high risk drinking rate 의 지역간 변이가 크고, quanile별로 관련요인을 다르다는 것을 파악하였습니다. 본 연구의 결과는 높은 지역의 스트레스와 조이혼율의 관리와 함께 지역 고위험음주율의 건강프로그램이 필요하다는 것을 암시한다.

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Age-period-cohort Analysis of Healthy Lifestyle Behaviors Using the National Health and Nutrition Survey in Japan: Tasuku Okui; J Prev Med Public Health. 2020;53(6):409-418. Published online August 13, 2020; DOI: https://doi.org/10.3961/jpmph.20.159

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Abstract PDF

Objectives
This study conducted an age-period-cohort (APC) analysis of trends in healthy lifestyle behaviors in Japan.
Methods
We used National Health and Nutrition Survey data on salt intake and prevalence of smoking, drinking, and physical activity between 1995 and 2018 in Japan. Age groups were defined from 20 years to 69 years old in 10-year increments. Cohorts were defined for each age group of each year with a 1-year shift, and cohorts born in 1926-1935 (first cohort) until 1989-1998 (last cohort) were examined. We conducted a Bayesian APC analysis, calculating estimated values for each behavior by age group, period, and cohort.
Results
Estimated salt intake decreased from cohorts born in the 1930s to the 1960s, but increased thereafter in both genders, and the magnitude of increase was larger for men. Estimated smoking prevalence increased in the cohorts starting from the 1930s for men and the 1940s for women, and then decreased starting in the cohorts born in the 1970s for both genders. Although estimated drinking prevalence decreased starting in the cohorts born in approximately 1960 for men, for women it increased until the cohorts born in approximately 1970. Estimated physical activity prevalence decreased starting in the cohorts born in the 1940s in both genders, but the magnitude of decrease was larger for women.
Conclusions
Trends in cohort effects differed by gender, which might be related to changes in the social environment for women. Improvements in dietary and exercise habits are required in more recently born cohorts of both genders.

Summary

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Interactions of Behavioral Changes in Smoking, High-risk Drinking, and Weight Gain in a Population of 7.2 Million in Korea: Yeon-Yong Kim, Hee-Jin Kang, Seongjun Ha, Jong Heon Park; J Prev Med Public Health. 2019;52(4):234-241. Published online July 3, 2019; DOI: https://doi.org/10.3961/jpmph.18.290

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Abstract Summary PDF

Objectives
To identify simultaneous behavioral changes in alcohol consumption, smoking, and weight using a fixed-effect model and to characterize their associations with disease status.
Methods
This study included 7 000 529 individuals who participated in the national biennial health-screening program every 2 years from 2009 to 2016 and were aged 40 or more. We reconstructed the data into an individual-level panel dataset with 4 waves. We used a fixed-effect model for smoking, heavy alcohol drinking, and overweight. The independent variables were sex, age, lifestyle factors, insurance contribution, employment status, and disease status.
Results
Becoming a high-risk drinker and losing weight were associated with initiation or resumption of smoking. Initiation or resumption of smoking and weight gain were associated with non-high-risk drinkers becoming high-risk drinkers. Smoking cessation and becoming a high-risk drinker were associated with normal-weight participants becoming overweight. Participants with newly acquired diabetes mellitus, ischemic heart disease, stroke, and cancer tended to stop smoking, discontinue high-risk drinking, and return to a normal weight.
Conclusions
These results obtained using a large-scale population-based database documented interactions among lifestyle factors over time.

Summary

Korean summary
이 분석은 흡연, 음주, 체중의 동시적 변화에 대해 패널분석방법론인 고정효과 모형을 이용하여 분석하였으며, 2009년부터 2016년까지 2년 주기로 4차례 모두 건강검진을 수검받은 720만 명을 대상으로 하였다. 흡연, 음주, 체중의 동시적 변화에 대한 방향성을 탐색하여 생활습관 관련 행태가 독자적이 아닌 유기적으로 변화하는 양상을 확인하였다, 또한 당뇨병, 뇌졸중, 암이 신규로 진단되었을 때 행태 변화가 나타나는 것을 확인하였다.

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The Korean Journal of Internal Medicine.2025; 40(6): 1017. CrossRef
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Perceptions About Alcohol Harm and Alcohol-control Strategies Among People With High Risk of Alcohol Consumption in Alberta, Canada and Queensland, Australia: Diana C. Sanchez-Ramirez, Richard C. Franklin, Donald Voaklander; J Prev Med Public Health. 2018;51(1):41-50. Published online December 30, 2017; DOI: https://doi.org/10.3961/jpmph.17.112

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Abstract PDF

Objectives
To explore alcohol perceptions and their association hazardous alcohol use in the populations of Alberta, Canada and Queensland, Australia.
Methods
Data from 2500 participants of the 2013 Alberta Survey and the 2013 Queensland Social Survey was analyzed. Regression analyses were used to explore the association between alcohol perceptions and its association with hazardous alcohol use.
Results
Greater hazardous alcohol use was found in Queenslanders than Albertans (p<0.001). Overall, people with hazardous alcohol were less likely to believe that alcohol use contributes to health problems (odds ratio [OR], 0.46; 95% confidence interval [CI], 0.27 to 0.78; p<0.01) and to a higher risk of injuries (OR, 0.54; 95% CI, 0.33 to 0.90; p<0.05). Albertans with hazardous alcohol use were less likely to believe that alcohol contributes to health problems (OR, 0.48; 95% CI, 0.26 to 0.92; p<0.05) and were also less likely to choose a highly effective strategy as the best way for the government to reduce alcohol problems (OR, 0.63; 95% CI, 0.43 to 0.91; p=0.01). Queenslanders with hazardous alcohol use were less likely to believe that alcohol was a major contributor to injury (OR, 0.39; 95% CI, 0.20 to 0.77; p<0.01).
Conclusions
Our results suggest that people with hazardous alcohol use tend to underestimate the negative effect of alcohol consumption on health and its contribution to injuries. In addition, Albertans with hazardous alcohol use were less in favor of strategies considered highly effective to reduce alcohol harm, probably because they perceive them as a potential threat to their own alcohol consumption. These findings represent valuable sources of information for local health authorities and policymakers when designing suitable strategies to target alcohol-related problems.

Summary

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Hazardous Alcohol Use in 2 Countries: A Comparison Between Alberta, Canada and Queensland, Australia: Diana C. Sanchez-Ramirez, Richard Franklin, Donald Voaklander; J Prev Med Public Health. 2017;50(5):311-319. Published online July 14, 2017; DOI: https://doi.org/10.3961/jpmph.17.040

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Abstract PDF

Objectives
This article aimed to compare alcohol consumption between the populations of Queensland in Australia and Alberta in Canada. Furthermore, the associations between greater alcohol consumption and socio-demographic characteristics were explored in each population. Methods: Data from 2500 participants of the 2013 Alberta Survey and the 2013 Queensland Social Survey were analyzed. Regression analyses were used to explore the associations between alcohol risk and socio-demographic characteristics. Results: A higher rate of hazardous alcohol use was found in Queenslanders than in Albertans. In both Albertans and Queenslanders, hazardous alcohol use was associated with being between 18 and 24 years of age. Higher income, having no religion, living alone, and being born in Canada were also associated with alcohol risk in Albertans; while in Queenslanders, hazardous alcohol use was also associated with common-law marital status. In addition, hazardous alcohol use was lower among respondents with a non-Catholic or Protestant religious affiliation. Conclusions: Younger age was associated with greater hazardous alcohol use in both populations. In addition, different socio-demographic factors were associated with hazardous alcohol use in each of the populations studied. Our results allowed us to identify the socio-demographic profiles associated with hazardous alcohol use in Alberta and Queensland. These profiles constitute valuable sources of information for local health authorities and policymakers when designing suitable preventive strategies targeting hazardous alcohol use. Overall, the present study highlights the importance of analyzing the socio-demographic factors associated with alcohol consumption in population-specific contexts.

Summary

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Special Article

Environmental Source of Arsenic Exposure: Jin-Yong Chung, Seung-Do Yu, Young-Seoub Hong; J Prev Med Public Health. 2014;47(5):253-257. Published online September 11, 2014; DOI: https://doi.org/10.3961/jpmph.14.036

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Abstract PDF

Arsenic is a ubiquitous, naturally occurring metalloid that may be a significant risk factor for cancer after exposure to contaminated drinking water, cigarettes, foods, industry, occupational environment, and air. Among the various routes of arsenic exposure, drinking water is the largest source of arsenic poisoning worldwide. Arsenic exposure from ingested foods usually comes from food crops grown in arsenic-contaminated soil and/or irrigated with arsenic-contaminated water. According to a recent World Health Organization report, arsenic from contaminated water can be quickly and easily absorbed and depending on its metabolic form, may adversely affect human health. Recently, the US Food and Drug Administration regulations for metals found in cosmetics to protect consumers against contaminations deemed deleterious to health; some cosmetics were found to contain a variety of chemicals including heavy metals, which are sometimes used as preservatives. Moreover, developing countries tend to have a growing number of industrial factories that unfortunately, harm the environment, especially in cities where industrial and vehicle emissions, as well as household activities, cause serious air pollution. Air is also an important source of arsenic exposure in areas with industrial activity. The presence of arsenic in airborne particulate matter is considered a risk for certain diseases. Taken together, various potential pathways of arsenic exposure seem to affect humans adversely, and future efforts to reduce arsenic exposure caused by environmental factors should be made.

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Journal of Food Quality.2021; 2021: 1. CrossRef
Oral Nigella sativa oil administration alleviates arsenic-induced redox imbalance, DNA damage, and metabolic and histological alterations in rat liver
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Environmental Science and Pollution Research.2021; 28(30): 41464. CrossRef
Seven potential sources of arsenic pollution in Latin America and their environmental and health impacts
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Science of The Total Environment.2021; 780: 146274. CrossRef
Metals associated neurodegeneration in Parkinson’s disease: Insight to physiological, pathological mechanisms and management
Khadga Raj, Pawandeep Kaur, G.D. Gupta, Shamsher Singh
Neuroscience Letters.2021; 753: 135873. CrossRef
Assessment of arsenic exposure in the population of Sabalpur village of Saran District of Bihar with mitigation approach
Arun Kumar, Rishav Kumar, Md. Samiur Rahman, Mohammad Ali, Ranjit Kumar, Neha Nupur, Aman Gaurav, Vikram Raj, Gautam Anand, Pintoo Kumar Niraj, Nirmal Kumar, Abhinav Srivastava, Akhouri Biswapriya, Gyanendra Bahadur Chand, Dhruv Kumar, Tuhin Rashmi, Santo
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Understanding Potential Heavy Metal Contamination, Absorption, Translocation and Accumulation in Rice and Human Health Risks
Zuliana Zakaria, Nur Syahirah Zulkafflee, Nurul Adillah Mohd Redzuan, Jinap Selamat, Mohd Razi Ismail, Sarva Mangala Praveena, Gergely Tóth, Ahmad Faizal Abdull Razis
Plants.2021; 10(6): 1070. CrossRef
Health impacts of indoor air pollution from household solid fuel on children and women
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Journal of Hazardous Materials.2021; 416: 126127. CrossRef
Toxic Elements in Traditional Kohl-Based Eye Cosmetics in Spanish and German Markets
Elisabet Navarro-Tapia, Mariona Serra-Delgado, Lucía Fernández-López, Montserrat Meseguer-Gilabert, María Falcón, Giorgia Sebastiani, Sebastian Sailer, Oscar Garcia-Algar, Vicente Andreu-Fernández
International Journal of Environmental Research and Public Health.2021; 18(11): 6109. CrossRef
A review on sources, identification and treatment strategies for the removal of toxic Arsenic from water system
B. Senthil Rathi, P. Senthil Kumar
Journal of Hazardous Materials.2021; 418: 126299. CrossRef
Recent Advances in Colorimetric Detection of Arsenic Using Metal-Based Nanoparticles
Haradhan Kolya, Kazuharu Hashitsume, Chun-Won Kang
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Continuous fixed-bed column studies of arsenite removal via oxidation and adsorption coprocesses
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Curcumin sensitizes Epstein‑Barr‑immortalized lymphoblastoid cell lines to inorganic arsenic toxicity
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The combination of phytoremediation and electrokinetics remediation technology on arsenic contaminated remediation in tailing storage facilities from gold mine
Kitsadee Wanitsawatwichai, Pantawat Sampanpanish
Heliyon.2021; 7(8): e07736. CrossRef
Hair Lead, Aluminum, and Other Toxic Metals in Normal-Weight and Obese Patients with Coronary Heart Disease
Anatoly V. Skalny, Philippe Yu Kopylov, Monica M. B. Paoliello, Jung-Su Chang, Michael Aschner, Igor P. Bobrovnitsky, Jane C.-J. Chao, Jan Aaseth, Sergei N. Chebotarev, Alexey A. Tinkov
International Journal of Environmental Research and Public Health.2021; 18(15): 8195. CrossRef
Design and Prototyping of Genetically Encoded Arsenic Biosensors Based on Transcriptional Regulator AfArsR
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Biomolecules.2021; 11(9): 1276. CrossRef
Arsenic Pathways in the Environment: The Role of Contaminated Groundwater in the Dispersion of Arsenic to Soil, Vegetables and Chicken Meat
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International Journal of Environmental Research.2021; 15(6): 921. CrossRef
Low Blood-As Levels and Selected Genotypes Appears to Be Promising Biomarkers for Occurrence of Colorectal Cancer in Women
Piotr Baszuk, Paulina Stadnik, Wojciech Marciniak, Róża Derkacz, Anna Jakubowska, Cezary Cybulski, Tomasz Huzarski, Jacek Gronwald, Tadeusz Dębniak, Katarzyna Białkowska, Sandra Pietrzak, Józef Kładny, Rodney J. Scott, Jan Lubiński, Marcin R. Lener
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Molecular Mechanism of Arsenic-Induced Neurotoxicity including Neuronal Dysfunctions
Manisha Thakur, Mahesh Rachamalla, Som Niyogi, Ashok Kumar Datusalia, Swaran Jeet Singh Flora
International Journal of Molecular Sciences.2021; 22(18): 10077. CrossRef
The toxicokinetic of arsenic in the edible and non-edible tissues of freshwater shellfish
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Environmental Technology & Innovation.2021; 24: 101940. CrossRef
Human Health Risk Assessment of Heavy Metals in the Urban Road Dust of Zhengzhou Metropolis, China
Muhammad Faisal, Zening Wu, Huiliang Wang, Zafar Hussain, Muhammad Imran Azam
Atmosphere.2021; 12(9): 1213. CrossRef
Photocatalytic Degradation of Organic, Inorganic and Microbial Pollutants Present in Water by Novel Materials: A Critical Review and Present Update
Elizabeth Kuruvilla, C. Freeda Christy, A. Samson Nesaraj
Asian Journal of Chemistry.2021; 33(10): 2251. CrossRef
Detoxification of Arsenic-Containing Copper Smelting Dust by Electrochemical Advanced Oxidation Technology
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Exposure to Environmental Arsenic and Emerging Risk of Alzheimer’s Disease: Perspective Mechanisms, Management Strategy, and Future Directions
Md. Rahman, Md. Hannan, Md Uddin, Md Rahman, Md Rashid, Bonglee Kim
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Hydrogeological studies and evaluation of surface and groundwater quality of Khyber Pakhtunkhwa, Pakistan
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Water contaminant levels interact with parenting environment to predict development of depressive symptoms in adolescents
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Blood arsenic levels and the risk of familial breast cancer in Poland
Wojciech Marciniak, Róża Derkacz, Magdalena Muszyńska, Piotr Baszuk, Jacek Gronwald, Tomasz Huzarski, Cezary Cybulski, Anna Jakubowska, Michał Falco, Tadeusz Dębniak, Marcin Lener, Oleg Oszurek, Katherine Pullella, Joanne Kotsopoulos, Ping Sun, Steven A.
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Ferulic acid attenuates arsenic‐induced cardiotoxicity in rats
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Neuropathological changes in wild muskrats (Ondatra zibethicus) and red squirrels (Tamiasciurus hudsonicus) breeding in arsenic endemic areas of Yellowknife, Northwest Territories (Canada): Arsenic and cadmium accumulation in the brain and biomarkers of o
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Developmental toxicity of arsenic: a drift from the classical dose–response relationship
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Arsenic: Geochemical distribution and age-related health risk in Italy
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Low concentrations of sodium arsenite induce hepatotoxicity in prepubertal male rats
Ricardo R. Samelo, Paloma da Cunha de Medeiros, Deborah N. de Carvalho Cavalcante, Maria L. G. Aranha, Fabio A. Duarte, Ítalo B. de Castro, Daniel A. Ribeiro, Juliana E. Perobelli
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Deciphering the molecular mechanism behind stimulated co-uptake of arsenic and fluoride from soil, associated toxicity, defence and glyoxalase machineries in arsenic-tolerant rice
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Journal of Hazardous Materials.2020; 390: 121978. CrossRef
Cycling and total risks of multiple As fractions in the Beijing–Tianjin–Hebei area on the agricultural plain, China
Kui Cai, Zefeng Song
Ecotoxicology and Environmental Safety.2020; 190: 110097. CrossRef
Arsenic in outdoor air particulate matter in China: Tiered study and implications for human exposure potential
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Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair
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The impact of biomass burning on the oxidative potential of PM2.5 in the metropolitan area of Milan
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Lei Jin, Jing-ru Yu, Le Zhang, Ai-guo Ren
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Biomimetic System for the Application of Nanomaterials in Fluid Purification: Removal of Arsenic with Ferrihydrite
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A Water‐Stable Ionic MOF for the Selective Capture of Toxic Oxoanions of SeVI and AsV and Crystallographic Insight into the Ion‐Exchange Mechanism
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A Water‐Stable Ionic MOF for the Selective Capture of Toxic Oxoanions of SeVI and AsV and Crystallographic Insight into the Ion‐Exchange Mechanism
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Arsenic Removal from Aqueous Solutions by Forward Osmosis
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Health risks from trace elements in muscles of some commonly available fish in Australia and India
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Environmental Chemistry Letters.2020; 18(4): 1145. CrossRef
Is Arsenic in Rice a Major Human Health Concern?
Jayanta Kumar Biswas, Manas Warke, Rupali Datta, Dibyendu Sarkar
Current Pollution Reports.2020; 6(2): 37. CrossRef
Curcumin alleviates arsenic-induced toxicity in PC12 cells via modulating autophagy/apoptosis
Md Shiblur Rahaman, Subrata Banik, Mahmuda Akter, Md Mostafizur Rahman, Md Tajuddin Sikder, Toshiyuki Hosokawa, Takeshi Saito, Masaaki Kurasaki
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Dietary exposure to total and inorganic arsenic via rice and rice-based products consumption
Neus González, Josep Calderón, Antoni Rúbies, Jaume Bosch, Isabel Timoner, Victòria Castell, Montse Marquès, Martí Nadal, José L. Domingo
Food and Chemical Toxicology.2020; 141: 111420. CrossRef
Interactions of arsenic metabolism with arsenic exposure and individual factors on diabetes occurrence: Baseline findings from Arsenic and Non-Communicable disease cohort (AsNCD) in China
Qiang Zhang, Yaxing Hou, Da Wang, Yuanyuan Xu, Huihui Wang, Juan Liu, Liting Xia, Yongfang Li, Naijun Tang, Quanmei Zheng, Guifan Sun
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Arsenic Concentrations in Ground and Surface Waters across Arizona Including Native Lands
M.C. Jones, J.M. Credo, J.C. Ingram, J.A. Baldwin, R.T. Trotter, C.R. Propper
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Accumulation of trace elements in selected fish and shellfish species from the largest natural carp fish breeding basin in Asia: a probabilistic human health risk implication
Abu Sayeed Shafiuddin Ahmed, Mohammad Belal Hossain, Sanjida Afrin Semme, Saad Mohammad Omar Faruque Babu, Kamal Hossain, Mohammad Moniruzzaman
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Polyphenol‐rich fraction ofAlchornea cordifolialeaf ameliorates arsenite‐induced infertility in male rats
Temitayo Olabisi Ajibade, Funsho Olakitike Olayemi
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Arsenic and Obesity: a Review of Causation and Interaction
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Synthesis of alginate–polycation capsules of different composition: characterization and their adsorption for [As(iii)] and [As(v)] from aqueous solutions
Cristopeer Thomas-Busani, José Andrei Sarabia-Sainz, Jaqueline García-Hernández, Tomás J. Madera-Santana, Luz Vázquez-Moreno, Gabriela Ramos-Clamont Montfort
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lncRNA OTUD6B-AS1 Exacerbates As2O3-Induced Oxidative Damage in Bladder Cancer via miR-6734-5p-Mediated Functional Inhibition of IDH2
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Oxidative Medicine and Cellular Longevity.2020; 2020: 1. CrossRef
Arsenic Methyltransferase and Methylation of Inorganic Arsenic
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Arsenic Exposure and Breast Cancer Risk: A Re-Evaluation of the Literature
Katherine Pullella, Joanne Kotsopoulos
Nutrients.2020; 12(11): 3305. CrossRef
Dose-response meta-analysis of arsenic exposure in drinking water and intelligence quotient
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Morpho-chemical characterization and source apportionment of potentially toxic metal(oid)s from school dust of second largest populous city of Pakistan
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Novel arsenic resistant bacterium Sporosarcina luteola M10 having potential bioremediation properties
Menaka Salam, Ajit Varma, Divya Chaudhary, Himanshi Aggarwal
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A Density Functional Theory Study on using Montmorillonite to Reduce Air Pollution
Triati Dewi Kencana Wungu, Meqorry Yusfi, Suprijadi Suprijadi
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Role of CTCF in DNA damage response
Vinay Singh Tanwar, Cynthia C. Jose, Suresh Cuddapah
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Ethnic, geographic and dietary differences in arsenic exposure in the multi-ethnic study of atherosclerosis (MESA)
Miranda R. Jones, Maria Tellez-Plaza, Dhananjay Vaidya, Maria Grau-Perez, Wendy S. Post, Joel D. Kaufman, Eliseo Guallar, Kevin A. Francesconi, Walter Goessler, Keeve E. Nachman, Tiffany R. Sanchez, Ana Navas-Acien
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Metal-air fuel cell electrocoagulation techniques for the treatment of arsenic in water
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A systematic review on global pollution status of particulate matter-associated potential toxic elements and health perspectives in urban environment
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Biomonitoring and health risks assessment of trace elements in various age- and gender-groups exposed to road dust in habitable urban-industrial areas of Hefei, China
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Synthesis and characterization of magnetic bio-adsorbent developed from Aegle marmelos leaves for removal of As(V) from aqueous solutions
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Impact of arsenic exposure on clinical biomarkers indicative of cardiovascular disease risk in Mexican women
Ángeles C. Ochoa-Martínez, Tania Ruiz-Vera, Claudia I. Almendarez-Reyna, Sergio Zarazúa, Leticia Carrizales-Yáñez, Iván N. Pérez-Maldonado
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Technology alternatives for decontamination of arsenic-rich groundwater—A critical review
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Arsenic(V) adsorption on ferric oxyhydroxide gel at high alkalinity for securely recycling of arsenic-bearing copper slag
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Tania Ruíz-Vera, Ángeles C. Ochoa-Martínez, Sergio Zarazúa, Leticia Carrizales-Yáñez, Iván N. Pérez-Maldonado
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Socioeconomic status and the association between arsenic exposure and type 2 diabetes
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Role of cadmium and arsenic as endocrine disruptors in the metabolism of carbohydrates: Inserting the association into perspectives
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Spatial distribution of arsenic in groundwater of Iran, a review
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Leaching Kinetics of Sulfides from Refractory Gold Concentrates by Nitric Acid
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Arsenic-Induced Neoplastic Transformation Involves Epithelial–Mesenchymal Transition and Activation of the β-Catenin/c-Myc Pathway in Human Kidney Epithelial Cells
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Arsenic accumulation in lentil (Lens culinaris) genotypes and risk associated with the consumption of grains
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Rice Consumption and Subclinical Lung Disease in US Adults: Observational Evidence From the Multi-Ethnic Study of Atherosclerosis
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American Journal of Epidemiology.2019; 188(9): 1655. CrossRef
Optimized extraction of inorganic arsenic species from a foliose lichen biomonitor
Eve M. Kroukamp, Taddese W. Godeto, Patricia B. C. Forbes
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Biological and molecular modifications induced by cadmium and arsenic during breast and prostate cancer development
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A Comprehensive Review of Microfluidic Water Quality Monitoring Sensors
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Estimating the risk of bladder and kidney cancer from exposure to low-levels of arsenic in drinking water, Nova Scotia, Canada
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Risk Assessment for Children Exposed to Arsenic on Baseball Fields with Contaminated Fill Material
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International Journal of Environmental Research and Public Health.2018; 15(1): 67. CrossRef
Aptamer-Based Impedimetric Assay of Arsenite in Water: Interfacial Properties and Performance
Karlene Vega-Figueroa, Jaime Santillán, Valerie Ortiz-Gómez, Edwin O. Ortiz-Quiles, Beatriz A. Quiñones-Colón, David A. Castilla-Casadiego, Jorge Almodóvar, Marvin J. Bayro, José A. Rodríguez-Martínez, Eduardo Nicolau
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Naiara Viana Campos, Samara Arcanjo-Silva, Larisse Freitas-Silva, Talita Oliveira de Araújo, Daniela Pinto Souza-Fernandes, Aristéa Alves Azevedo
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Highly-efficient removal of AsV, Pb2+, Fe3+, and Al3+ pollutants from water using hierarchical, microscopic TiO2 and TiOF2 adsorbents through batch and fixed-bed columnar techniques
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Geochemical Characteristics of Soils on Ellis Island, New York-New Jersey, Sixty Years after the Abandonment of the Hospital Complex
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Geosciences.2018; 8(1): 13. CrossRef
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International Journal of Molecular Sciences.2018; 19(4): 1026. CrossRef
Functional manganese ferrite/graphene oxide nanocomposites: effects of graphene oxide on the adsorption mechanisms of organic MB dye and inorganic As(v) ions from aqueous solution
Pham Thi Lan Huong, Nguyen Tu, Hoang Lan, Le Hong Thang, Nguyen Van Quy, Pham Anh Tuan, Ngo Xuan Dinh, Vu Ngoc Phan, Anh-Tuan Le
RSC Advances.2018; 8(22): 12376. CrossRef
Environmental Influences on the Epigenome: Exposure- Associated DNA Methylation in Human Populations
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Original Articles

Associations Between Socio-demographic Characteristics and Healthy Lifestyles in Korean Adults: The Result of the 2010 Community Health Survey: So Yeon Ryu, Jong Park, Seong Woo Choi, Mi Ah Han; J Prev Med Public Health. 2014;47(2):113-123. Published online March 31, 2014; DOI: https://doi.org/10.3961/jpmph.2014.47.2.113

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Abstract PDF

Objectives

Several previous studies have found that healthy behaviors substantially reduce non-communicable disease incidence and mortality. The present study was performed to estimate the prevalence of four modifiable healthy behaviors and a healthy lifestyle among Korean adults according to socio-demographic and regional factors.

Methods

We analyzed data from 199 400 Korean adults aged 19 years and older who participated in the 2010 Korean Community Health Survey. We defined a healthy lifestyle as a combination of four modifiable healthy behaviors: non-smoking, moderate alcohol consumption, regular walking, and a healthy weight. We calculated the prevalence rates and odds ratios of each healthy behavior and healthy lifestyle according to socio-demographic and regional characteristics.

Results

The prevalence rates were as follows: non-smoking, 75.0% (53.7% in men, 96.6% in women); moderate alcohol consumption, 88.2% (79.7% in men, 96.9% in women); regular walking, 45.0% (46.2% in men, 43.8% in women); healthy weight, 77.4% (71.3% in men, 73.6% in women); and a healthy lifestyle, 25.5% (16.4% in men, 34.6% in women). The characteristics associated with a low prevalence of healthy lifestyle were male gender, younger age (19 to 44 years of age), low educational attainment, married, living in a rural area, living in the Chungcheong, Youngnam, or Gwangwon-Jeju region, and poorer self-rated health.

Conclusions

Further research should be implemented to explore the explainable factors of disparities for socio-demographic and regional characteristics to engage in the healthy lifestyle among adults.

Summary

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Drinking Patterns Among Korean Adults: Results of the 2009 Korean Community Health Survey: So Yeon Ryu, Catherine M. Crespi, Annette E. Maxwell; J Prev Med Public Health. 2013;46(4):183-191. Published online July 31, 2013; DOI: https://doi.org/10.3961/jpmph.2013.46.4.183

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Abstract PDF

Objectives

In Korea, the proportion of deaths due to alcohol is estimated at 8.9%, far exceeding the global estimate of 3.8%. Therefore, this study was performed to examine the factors associated with low-risk, moderate-risk, and high-risk drinking patterns in Korean adults and to identify target populations for prevention and control of alcohol-related diseases and deaths.

Methods

We analyzed data from 230 715 Korean adults aged 19 years and older who participated in the 2009 Korean Community Health Survey. Multinomial logistic regression analysis was used to examine associations between socio-demographic and health-related factors and patterns of alcohol use.

Results

A substantially larger proportion of men than women engaged in high risk (21.2% vs. 3.4%) and moderate-risk alcohol use (15.5% vs. 8.2%). In both sexes, moderate- and high-risk uses were associated with younger age, higher income, being currently employed, smoking, being overweight/obese, and good self-rated health.

Conclusions

Given the large proportion of the population that is engaging in moderate- and high-risk drinking and given the social norms that support this behavior, public health policies and campaigns to reduce alcohol consumption targeting the entire population are indicated.

Summary

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Special Article

Burden of Noncommunicable Diseases and National Strategies to Control Them in Korea: Young-Ho Khang; J Prev Med Public Health. 2013;46(4):155-164. Published online July 31, 2013; DOI: https://doi.org/10.3961/jpmph.2013.46.4.155; Correction in: J Prev Med Public Health 2013;46(5):292

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Abstract PDF

Noncommunicable diseases (NCDs) are the most important causes of premature mortality and disability-adjusted life years in Korea. NCDs are also the main contributor to socioeconomic inequalities in mortality and life expectancy. Reduction of NCDs and NCD inequalities would result in significant improvement in healthy life expectancy and health equity in Korea. Major NCD risk factors such as dietary risks (including salt intake), alcohol consumption, cigarette smoking, and high blood pressure were found to be the leading modifiable risk factors of disability-adjusted life years in Korea, based on the 2010 Global Burden of Disease Study. Several Korean studies have shown that these risk factors play an important role in creating socioeconomic inequalities in NCD mortality and total mortality. Current international discussions on NCD policies in the United Nations and the World Health Organization would provide better opportunities for developing aggressive population-wide policy measures in Korea. Considering the paucity of population-wide policies to control major NCD risk factors in Korea, rigorous population approaches such as taxation and regulation of unhealthy commodities as well as public education and mass campaigns should be further developed in Korea.

Summary

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Original Article

Alcohol Consumption and Mortality in the Korean Multi-center Cancer Cohort Study: En-Joo Jung, Aesun Shin, Sue K. Park, Seung-Hyun Ma, In-Seong Cho, Boyoung Park, Eun-Ha Lee, Soung-Hoon Chang, Hai-Rim Shin, Daehee Kang, Keun-Young Yoo; J Prev Med Public Health. 2012;45(5):301-308. Published online September 28, 2012; DOI: https://doi.org/10.3961/jpmph.2012.45.5.301

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Abstract PDF

Objectives

To examine the association between alcohol consumption habit, types of beverages, alcohol consumption quantity, and overall and cancer-specific mortality among Korean adults.

Methods

The alcohol consumption information of a total of 16 320 participants who were 20 years or older from the Korean Multi-center Cancer Cohort were analyzed to examine the association between alcohol consumption habit and mortality (median follow-up of 9.3 years). The Cox proportional hazard model was used to estimate the hazard ratio (HR) of alcohol consumption to mortality adjusting for age, sex, geographic areas, education, smoking status, and body mass index.

Results

Alcohol drinkers showed an increased risk for total mortality compared with never drinkers (HR, 1.72; 95% confidence interval [CI], 1.38 to 2.14 for past drinkers; HR, 1.21; 95% CI, 1.06 to 1.39 for current drinkers), while past drinkers only were associated with higher risk for cancer deaths (HR, 1.84; 95% CI, 1.34 to 2.53). The quantity of alcohol consumed per week showed a J-shaped association with risk of mortality. Relative to light drinkers (0.01 to 90 g/wk), never drinkers and heavy drinkers (>504 g/wk) had an increased risk for all-cause and cancer deaths: (HR, 1.18; 95% CI, 0.96 to 1.45) and (HR, 1.39; 95% CI, 1.05 to 1.83) for all-cause mortality; and (HR, 1.55; 95% CI, 1.15 to 2.11) and (HR, 2.07; 95% CI, 1.39 to 3.09) for all cancer mortality, respectively. Heavy drinkers (>504 g/wk) showed an elevated risk for death from stomach and liver cancers.

Conclusions

The present study supports the existence of a J-shaped association between alcohol consumption quantity and the risk of all-cause and cancer deaths. Heavy drinkers had an increased risk of death from cancer overall and liver and stomach cancer.

Summary

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English Abstracts

Estimating the Socioeconomic Costs of Alcohol Drinking Among Adolescents in Korea.: Jaeyeun Kim, Woojin Chung, Sunmi Lee, Chongyon Park; J Prev Med Public Health. 2010;43(4):341-351.; DOI: https://doi.org/10.3961/jpmph.2010.43.4.341

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Abstract PDF

OBJECTIVES
The purpose of this study was to estimate the socioeconomic costs resulting from alcohol drinking among adolescents as of 2006 from a societal perspective. METHODS: The costs were classified into direct costs, indirect costs, and other costs. The direct costs consisted of direct medical costs and direct non-medical costs. The indirect costs were computed by future income losses from premature death, productivity losses from using medical services and reduction of productivity from drinking and hangover. The other costs consisted of property damage, public administrative expenses, and traffic accident compensation. RESULTS: The socioeconomic costs of alcohol drinking among adolescents as of 2006 were estimated to be 387.5 billion won (0.05% of GDP). In the case of the former, the amount included 48.25% for reduction of productivity from drinking and hangover, 39.38% for future income losses from premature death, and 6.71% for hangover costs. CONCLUSIONS: The results showed that the socioeconomic costs of alcohol drinking among adolescents in Korea were a serious as compared with that of the United States. Therefore, the active interventions such as a surveillance system and a prevention program to control adolescents drinking by government and preventive medicine specialist are needed.

Summary

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Cohort Study on the Association between Alcohol Consumption and the Risk of Colorectal Cancer in the Korean Elderly.: Hoi Jeong Lim, Byung Joo Park; J Prev Med Public Health. 2008;41(1):23-29.; DOI: https://doi.org/10.3961/jpmph.2008.41.1.23

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Abstract PDF

OBJECTIVES
We examined the association between alcohol consumption and incidence of colorectal cancer in elderly Koreans. METHODS: The cohort members (n=14,304) consisted of 4,834 males and 9,470 females derived from the Korea Elderly Pharmacoepidemiologic Cohort (KEPEC), a population-based dynamic cohort. They were aged 65 years old or older and lived in Busan between 1993-1998; they were beneficiaries of the Korean Medical Insurance Corporation (KMIC). Baseline information was surveyed by a self-administered, mailed questionnaire. This study population was restricted to 14,304 participants who reported alcohol drinking habits on the questionnaire and had not been diagnosed with colorectal cancer at baseline. The adjusted hazard ratios (aHR) of status, type, frequency and daily average amount of alcohol consumption were computed with Cox's proportional hazard model, with the never-drinkers as a reference group and controlling for age and gender. RESULTS: After 4.82 person-years of mean follow-up 112 cases of colorectal cancer occurred. The incidence densities of colorectal cancer were 161 (95% CI=123-200) for never-drinkers, 219 (95% CI=125-339) for ex-drinkers, and 137 (95% CI=84-189) for current-drinkers per 100,000 person-year. The status, type, frequency, and daily average amount of alcohol consumption were not significantly related to the incidence of colorectal cancer after controlling for age and gender. CONCLSIONS: There was no significant association between alcohol consumption and colorectal cancer among elderly people after controlling for age and gender.

Summary

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Multicenter Study

Cigarette Smoking, Alcohol Consumption, Tuberculosis and Risk of Lung Cancer: The Korean Multi-center Cancer Cohort Study.: Jisuk Bae, Jin Gwack, Sue Kyung Park, Hai Rim Shin, Soung Hoon Chang, Keun Young Yoo; J Prev Med Public Health. 2007;40(4):321-328.; DOI: https://doi.org/10.3961/jpmph.2007.40.4.321

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Abstract PDF

OBJECTIVES
The aim of this study was to evaluate the roles of cigarette smoking, alcohol consumption, tuberculosis, and their interactions in the risk of lung cancer in a Korean cohort. METHODS: The study subjects comprised 13,150 males and females aged above 20 years old. During the follow up period from 1993 to 2002, 79 lung cancer cases were identified by the central cancer registry and the national death certificate database. Information on cigarette smoking, alcohol consumption and the history of physiciandiagnosed tuberculosis was obtained by interview. Indirect chest X-ray findings were also evaluated to ascertain tuberculosis cases. Cox proportional hazard models were used to estimate relative risks (RR) and 95% confidence intervals (CI) after adjusting for age and gender. RESULTS: Cigarette smoking was statistically significantly associated with an increased risk of lung cancer [for current smokers, RR = 2.33 (95% CI = 1.23 - 4.42) compared to non-smokers]. After further adjustment for cigarette smoking, both alcohol consumption and tuberculosis showed no statistically significant association with the risk of lung cancer [for current drinkers, RR = 0.80 (95% CI = 0.48 - 1.33) compared to non-drinkers] [for tuberculosis cases, RR = 1.17 (95% CI = 0.58 - 2.36) compared to noncases]. There was no statistically significant interaction between cigarette smoking and alcohol consumption (pinteraction = 0.38), or cigarette smoking and tuberculosis (p-interaction = 0.74). CONCLUSIONS: Although cigarette smoking was confirmed as a risk factor of lung cancer in this cohort study, this study suggests that alcohol consumption and tuberculosis may not be associated with the risk of lung cancer.

Summary

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Original Articles

Prevalence of Hazardous and Harmful Alcohol Consumption Using Alcohol Use Disorders Identification Test in Chungju Area.: Hyeongsu Kim, Sounghoon Chang, Kunsei Lee, Cheongsik Kim, Kiock Kim; Korean J Prev Med. 2001;34(3):277-283.

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Abstract PDF: OBJECTIVES
To investigate the prevalence of hazardous and harmful alcohol use, which are a subthreshold of alcohol related disorders. METHODS: Direct-interview questionnaires to 1,183 rural persons (489 male, 694 female) were conducted in Chungju-city from July 2 to 26, 1998. As a screening instrument, the alcohol use disorders identification test (AUDIT) was used. RESULTS: The prevalence of alcohol use was 41.7%. In males, it was 66.3% and in females, it was 24.4%. The mean of the AUDIT score of males and females was 13.2 and 5.6, respectively. As WHO guideline, the prevalence of hazardous alcohol use in males and females was 80.3% and 20.7%, respectively. This suggests that the prevalence of 'hazardous drinking' and 'harmful drinking' was 45.4% and 29.3% for males and 1.2% and 2.4% for females, respectively. CONCLUSIONS: This study presented the prevalence of hazardous and harmful drinking of a rural population in Korea and reviewed those health problems. Further evaluation to detect and treat lower alcoholic drinkers is recommended; Summary

The Risk Factors Associated with Increased Blood Pressure, Sugar and Lipids in Multi-phasic Health Checkup Examinee.: Kang Sook Lee, Sang Deog Cho, Hyun Sook Hong; Korean J Prev Med. 2000;33(1):69-75.

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Abstract PDF: OBJECTIVES
This study was conducted to evaluate the risk factors associated with cardiovascular disease. METHODS: By the questionnaire, the informations of education level, monthly income, alcohol consumption and smoking habit were obtained. Height, weight and blood pressure(BP) were measured by a trained nurse. The level of fasting blood sugar(FBS), total cholesterol, hight-density lipoprotein(HDL) cholesterol and triglyceride were tested by enzyme method about a group of 2888 males and 1696 females ages over 20 who had never taken the medication for hypertension. Statistical analysis, ANOVA, stepwise multiple regression, correlation analysis were performed using SAS package program. RESULTS: There were significant differences among age groups in systolic and diastolic blood pressure, body mass index(BMI), FBS, triglyceride and cholesterol except HDL-cholesterol. The risk factors associated with systolic and diastolic BP significantly in male were BMI, age, alcohol intake, but in female BMI, age. Smoking habit had a significant negative correlation with BP in both sex. In the group of mild hypertension (> or =140 mmHg or> or =90 mmHg defined by JNC-VI) and hypertension (> or =160 mmHg or > or = 95 mmHg defined by WHO), the percent of diabetes (FBS> or =140 mg/dl), hypercholesterolemia (> or =240 mg/dl), and hypertriglyceridemia (> or =200 mg/dl) were signifcantly higher compared with normal group in male and female. BMI, and alcohol consumption had a positive correlation with FBS, total cholesterol and triglyceride. Smoking had a positive correlation with cholesterol and triglyceride but negative correlation with HDL-cholesterol in male. The educational attainment had a negative correlation with BMI, FBS, total cholesterol and triglyceride in female. CONCLUSIONS: This study suggested that drinking, smoking, and BMI and lower educational level were associated with hypertension, hyperlipidemia and diabetes, but further evaluation was needed by prospective intervention study.; Summary

The effect of smoking and drinking habit on the health status of lead workers.: Choong Koo Lee, Yong Bae Kim, Gap Soo Lee, Kyu Yoon Hwang, Hwa Sung Kim, Sung Soo Lee, Kyu Dong Ahn, Byung Kook Lee; Korean J Prev Med. 1998;31(4):708-718.

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Abstract PDF: To investigate the effect of smoking and drinking habit on the health status in lead using industries, 2,785 male workers in lead using industries (7 storage battery industries, 7 secondary smelting and related industries, and 4 primary metal and other manufacturing industries) were selected for this study. This study was carried out as a part of periodic health examination. Selected study variables were zinc protoporphyrin in whole blood (ZPP), SGOT and SGPT for laboratory test. Questionnaire for lead related symptoms and smoking and drinking habit was provided to all the workers and filled up by themselves and reconfirmed by physician. The results obtained were as follows; 1. The overall smoking and drinking rate of study population were 69.8% and 73.6%, respectively. While the smoking and drinking rate of storage battery workers were 68.8% and 72.3%, those of secondary smelting industries and other industries were 66.0% and 66.4% and 74.6 and 80.3% respectively. 2. While the mean values of blood ZPP of lead exposed workers were significantly higher than other group, those of SGOT of storage battery workers were significant higher than other worker. But there were no differences of mean values of other variables. 3. Smoking habit did not affect on the mean value of blood ZPP of workers in special health examination group, but there were significant differences of blood ZPP and SGOT between drinker and non-drinker. 4. Symptom prevalence of lead exposure were higher in drinking and smoking group than non-drinking and non-smoking group. 5. In multiple regression analysis of the total lead related symptoms, blood ZPP, SGOT, and SGPT as dependent variable, respectively, and age, work duration, blood ZPP, pack year and amount of alcohol drinking as independent variables, work duration, pack year, amount of alcohol drinking, age contributed to total symptoms; and age, work duration, pack year contributed to blood ZPP; and age, amount of alcohol drinking, work duration contributed to SGOT; and pack year contributed to SGPT.; Summary

A Study on the Factors related to the Cognitive Impairment of the Elderly in a Rural Area.: Kwang Wook Koh, Byung Mann Cho, Su lll Lee, Don Kyoun Kim, Bong Su Cho, Yeung Wook Kim, Young Sil Kim, Su Yong Kang; Korean J Prev Med. 1996;29(3):657-668.

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Abstract PDF: To investigate the factors which affecting the cognitive impairment of the 60 or more age group, the authors surveyed for the subjects in some area of Kyungnam Province. 201 studied subjects were tested for cognitive function with mini-mental state examination(MMSE). Information on demographic characteristics and life style has been collected through direct interview. The concentration of Al and Ca of subject's drinking water, which might be related with cognition, was measured by Inductively Coupled Argon Plasma Spectrometer. The main results were summarized as follows. 1. The prevalence rate of cognitive impairment was 18.4% in male and 45.2% in female and this sexual difference was statistically significant(p=0.03). And the uneducated or illiterated showed significantly high prevalence rate of cognitive impairment(p=0.02). 2. In stratified analysis by sex and education year, we can not see significant trend indicating the neurotoxic effects of aluminum and protective effects of calcium to the cognitive function(p>0.05). 3. The correlation between the concentration of aluminum in drinking water and the MMSE score in whole subjects showed weak negative relationship(r=-0.066). But there was no statistical significance(p=0.434).; Summary

A Survey on Health Behavior of Male Workers in Steel Industry.: Eun Hee Ha, Hyun Sul Lim, Cha Hyung Wie, Jung Ok Kwak; Korean J Prev Med. 1996;29(1):113-132.

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Abstract PDF: This study was carried out to evaluate the relations among workers' general characteristics, work-related behaviors and health related behaviors in a steel industry with 1,134 workers in Pohang. The results were as follows; 1. The mean age of workers was 50 years old and working duration was 15 years and over. Most of them were married(94 5%) and had studied beyond high school (53.0%). They performed three shift work and most of them(63.0%) had experienced industrial accidents. The frequency of noise and dust exposure was defined by a minimum of 6 hours per day, and workers complained about noise exposure(62.9%) and dust(55.6%). There were current smokers(67.7%), current drinkers(74.3%) and current exercising workers(32.3%) in the industry. The number of cigarette consumption in current drinkers was significantly high (13.6 +/- 8.4 pieces/day) and the alcohol consumption in current smokers was significantly high(l04.5 +/- 113.5 g/wk). And the number of cigarette consumption of exercisers was significantly low and the alcohol consumption of exercisers was higher than non-exercisers. 3. The ratio of current smokers on frequent noise in exposed workers versus non-exposed workers was not significantly high but the current drinkers in frequent noise and dust exposed workers was significantly higher than non--exposed. 4. The normal levels of SGOT workers in non-smokers were significantly higher than in current smokers, and the abnormal levels of LFT(SGOT, SGPT, gamma-GTP workers in nondrinkers were significantly high. The normal levels of SBP and DBP workers in current smokers were not significantly high but were significantly high in non-drinkers. 5. The ratio of current smokers in workers unsatisfied with their job and working condition was higher than non-smokers, but the ratio of current drinkers in workers satisfied with their job and working condition were higher. 6. The significant factors for SGOT and gamma-GTP were age, the drinking amount and BMI. But the only significant factor for r-GTP was BMI. The significant factors for DBP were age, the alcohol consumption and BMI And the significant factors for SBP were age, BMI.; Summary

Study on the lead exposure of workers in a litharge making industry.: Sang Bok Lim, Jung Kyu Lim, Sung Soo Lee, Kyu Dong Ahn, Byung Kook Lee; Korean J Prev Med. 1995;28(4):875-884.

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Abstract PDF: In order to investigate the level of lead exposure of workers in litharge making industry and to evaluate how lead exposure, personal habit such as smoking and drinking affect the prevalence of lead related symptoms and other study variables, we investigate 114 workers(24 office workers and 90 lead exposed workers) in a litharge making industry. Study variables chosen were blood lead(PbB), zinc protoporphyrin in whole blood(ZPP), Hemoglobin(Hb), hematocrit (Hct), SGOT and SGPT. symptom questionnaires which had 15 lead exposure related symptoms were provided to all workers and filled up by themselves and reconfirmed by physician. The results obtained were as follows; 1. The mean value of PbB, ZPP and SGOT in lead exposed group were higher than those of non-exposed group, and there were no differences of means in other study variables. 2. The smoking and drinking rate of study subjects were 65.8% and 71.0% as a whole. Smoking rates were lower in non-exposed group than exposed group, but drinking rate were not. 3. There were no differences of mean values of study variables between smoker and non-smoker in non-exposed and exposed group, but there was a difference of mean value of SGOT between drinker and non-drinker in lead exposed group. 4. while the symptom prevalence of lead exposed group were higher in neuromuscular category than non-exposed group, those of non-exposed group were higher or same with exposed group in gastrointestinal and general symptom category. 5. The symptom prevalence of smoker were higher than non-smoker regardless of exposure. 6. The symptom prevalence of drinker were only higher in gastrointestinal symptom category than non-drinker. 7. In multiple stepwise regression analysis of lead related symptoms as dependent variable and blood lead, smoking habit, drinking habit and work duration as independent variables, drinking habit contributed to the gastrointestinal symptom category, whereas blood lead and smoking contributed to the neuromuscular symptom category. For the total symptoms work duration and smoking habit contributed significantly.; Summary

A study on the concentration and health risk of trihalomethanes in drinking water.: Yong Chung, Dong Chun Shin, Bo Young Lee, Sung Han Yu, Sang Hyuk Chung; Korean J Prev Med. 1989;22(4):495-505.

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Abstract PDF: This study was conducted as a nationwide survey in Korea to determine the THM (trihalomethane) concentration levels in the drinking water of 14 selected cities. The survey was undertaken in one city (Kwangju) during September and October of 1988 and 14 cities in January through February of 1988. The results were as follows: 1. The KMnO4 consumption was 10.6 mg/l - 11.6 mg/l in Pusan and Ulsan, exceeding the drinking water standard of 10 mg/l. Pusan, Inchon, Kwangju, Ulsan, Mokpo and Junju areas also exceeded the ammonia nitrate standard of 0.5 mg/l, Other tap waters surveyed were detected below the drinking water standards. 2. The THM concentrations of tap water measured in January and February of 1989 were detected in the range 1.20 microgram/l - 150.8 microgram/l. 3. In the comparative study of the THM concentration of tap water measured in the Kwangju area during September and October of 1988, the average THM concentration of 145.63 +/- 70.72 microgram/l showed a sifford increase compared to that of 23.8 +/- 8.31 microgram/l surveyed in January and February 1989. 4. The proportion of the four THM compounds found in tap water was bromoform, 47%; chloroform, 30%; chlordibromomethane, 13%; and dichlorobromomethane, 10%. 5. Since the results indicate that the concentration of bromoform was 2 - 10 times higher than that of chloroform measured in the seaside district of Pusan, Ulsan and Cheju Island, it is reasonable to assume that the raw water was somehow influenced by seawater. 6. The average lifetime cancer rate of the population exposed to chloroform measured in the surveyed areas was 17 cancer incidences per 1 million population. From the above results, the existence of THM in the distribution systems seems to be inevitable, since chlorine disinfection is performed in water treatment plants in our country. There seems to be a trend of increasing. THM concentrations due to the contamination of raw water. In order to establish any form of regulations, health risk assessment is an imminent subject.; Summary

Case Report

Mass paraquat poisoning in a small island community: case report.: Sung Woo Lee, Tae Wha Chung, Kang Won Choi, Jung Ki Lim, Duk Hyoung Lee; Korean J Prev Med. 1989;22(4):454-465.

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Abstract PDF: In a small island community with a population of less than 100 residents, nine persons died and five experienced severe illness during the period from November 1986 to May 1988. Their initial symptoms were sore throat and fever. Renal failure and hepatitis developed which one week after the onset. Oral mucosal ulcer developed in some cases. After one week, progressive respiratory failure and dyspnea developed evidently and severe respiratory distress and hypoxia preceded those fatal cases. Chest X-ray findings revealed bilateral diffuse multiple cystic lesion with occasional multiple large emphysematous bullae. Based on these features paraquat poisoning was diagnosed and route of poisoning was investigated. In three sources of drinking water, trace amount of paraquat was detected in November 1988, six months after the incidence of recent fatal case. In November 1988, soybean sauces and soybean pastes from 12 households were found contaminated with high concentration of paraquat, the cause of this mass poisoning has been suggested.; Summary

Original Articles

Effect of Drinking and Smoking on AST and ALT Activities.: Doohie Kim, Seol Seo; Korean J Prev Med. 1988;21(2):329-339.

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Abstract PDF: The study is carried out to investigate the effect of drinking and smoking for the activities of aspartate aminotransferse(AST, or GOT) and alanine amintransferse(ALT or GPT), from December 25, 1986 to April 30, 1987. The male physical examinees for employment, 900 who had visited to the Taegu Medical Center were subjected. And the positive cases of HBs-Ag, Anti-HBs and skin test for Clonorchis sinensis were excluded. The general characters of drinking and smoking pattern were introduced by interview with questionnaire provided for. In drinking cases, the longer duration was significantly effected the higher rate of abnormality in AST and ALT level. But the amount and the frequency were not. It was not appeared effects by mackgulri which is a Korean traditional wine and small amount of beers. In smoking cases, also same pattern. The age was related in all cases. By the way, when the effect is related the positive results with other factors; HBs-Ag, Anti-HBs, skin test for clonorchiasis and harmful occupational history, it is higher abnormal rate of AST and ALT in the duplicated cases with two factors or more. Particularly in HBs-Ag positive cases, those who had smoking was the highest in rate of abnormality, and drinking was the follows. In correlation matrix among seven factors; HBs-Ag, age, drinking amount, drinking period, drinking frequency, smoking amount and smoking period, correlation coefficient was significant between the abnormal rate and to with age, drinking period, smoking period, and smoking amount.; Summary

Mutagenic Activity of Organic Pollutans in Drinking Water in Seoul.: Dong Chun Shin, Jae Yeon Jang, Seong Joon Jo, Yong Chun; Korean J Prev Med. 1988;21(2):284-294.

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Abstract PDF: To measure the mutagenic activity of micro-organic pollutants in drinking water, mutagenic test was conducted using Salmnella typhimurium TA 98 strain on the water sample taken from three water supply station and six tap water in Seoul in July and November 1987. The results were as follows : 1. The average amounts of organic matters in raw, treated, and tap water sampled in July were 0.38mg/l, 0.28mg/l, and 0.45mg/l, respectively, and sampled in November were 0.34mg/l, 0.24mg/l, and 0.22mg/l, respectively. The amount of organic matters of tap water sampled in November did not increase while that of tap water sampled in July increased compare to those of raw or treated water. 2. The amount of organic matters is the highest in neutral fraction compare to acidic and basic fractions. 3. In the five out of six tap water and raw water of Paldang and Kuui station sampled in July, the mutagenic ratios were greater than two (both direct and indirect mutagenicity). 4. In the three out six tap water and raw and treated water of Kuui station sampled in November, the mutagenic ratios were greater than two. 5. While mutagenic were low in acidic and basic fraction, they were high in neutral fraction. The samples which had high mutagenic activity in the total amount also showed high mutagenic activity in neutral fraction. 6. While mutagenic activity was decreased after the treatment of water, it was increased in tap water as the distance from the water supply station increases.; Summary

English Abstracts

Socioeconomic Costs of Alcohol Drinking in Korea.: Woo Jin Chung, Hyun Jun Chun, Sun Mi Lee; J Prev Med Public Health. 2006;39(1):21-29.

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Abstract PDF: OBJECTIVES
We wanted to estimate the annual socioeconomic costs of alcohol drinking in Korea. METHODS: The costs were classified as direct costs, indirect costs and the other costs. The direct costs consisted of direct medical costs, indirect medical costs and subsidiary medical costs. Particularly, the medical costs and population attributable fraction for disease were considered to reflect the calculation of the direct medical costs. The indirect costs were computed by the extent to which the loss of productivity and loss of the workforce might have occurred due to changes in mortality and morbidity according to alcohol drinking. The other costs consisted of property loss, administration costs and costs of alcoholic beverage. RESULTS: The annual costs, which seemed to be attributable to alcohol drinking, were estimated to be 149,352 hundred million won (2.86% of GDP). In case of the latter, the amount includes 9,091 hundred million won for direct costs (6.09%), 62,845 hundred million won for the reduction and loss of productivity (42.08%), 44,691 hundred million won for loss of the workforce (29.92%), and the other costs (21.91%). CONCLUSIONS: Our study confirms that compared with the cases of Japan (1.9% of GNP) and the other advanced countries (1.00-1.42% of GDP), alcohol drinking incurs substantial socioeconomic costs to the Korean society. Therefore, this study provides strong support for government interventions to control alcohol drinking in Korea.; Summary

Correlates of Problem Drinking by the Alcohol Use Disorders Identification Test on Korean College Campus.: Sung soo Chun, Ae ree Sohn; J Prev Med Public Health. 2005;38(3):307-314.

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Abstract PDF: OBJECTIVE
To survey college students with an Alcohol Use Disorder, and analyze the reasons for their disorder. METHODS: The cross-sectional study was conducted at 60 four-year colleges within Seoul and 9 other provinces. The schools and students selected for the study provide a nationally representative sample, and the survey was conducted between May 15th and June 14th 2003. 2, 385 cases were analyzed using questionnaires, which included a series of questions about students' alcohol use and associated problems, as well as an Alcohol Use Disorder Identification Test. RESULTS: 42.3% of students were found to have an Alcohol Use Disorder. The probability of a student having an Alcohol Use Disorder was 1.30 times higher among male compared to female students. Those students not living with their parents or relatives were 1.40 times more likely to have an Alcohol Use Disorder. Those students where the father had a drinking problem and those who admitted that their parents drank heavily while they were growing up were 1.38 and 1.54 times more likely, respectively, to have an Alcohol Use Disorder. Those students attending a general university, joining a student club, attaining less than a B average credit score and those unsatisfied with their education were 1.60, 1.36, 1.41 and 1.27 times more likely, respectively, to have an Alcohol Use Disorder. Those students who had experience of drugs, smoking, binge drinking when they were in the last year of high school and the forceful consumption of mixed alcohol were 3.67, 1.95, 2.15 and 1.76 times more likely, respectively, to have an Alcohol Use Disorder. CONCLUSIONS: College students' with an Alcohol Use Disorder is a very severe and large problem within colleges. An Alcohol Use Disorder is determined by individual and family variables, the college environmental and life variables, as well as behavior variables.; Summary

The Association between Serum GGT Level within Normal Range and Risk Factors of Cardiovascular Diseases.: Ji Seun Lim, Yu Jin Kim, Byung Yeol Chun, Jin Hoon Yang, Duk Hee Lee, Sin Kam; J Prev Med Public Health. 2005;38(1):101-106.

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Abstract PDF: OBJECTIVES
We conducted this study to examine the association between serum GGT levels within the normal range and the risk factors of cardiovascular diseases METHODS: We examined the cross-sectional association between serum GGT and the systolic and diastolic blood pressure, fasting blood glucose, total cholesterol, triglyceride, high density lipoprotein cholesterol (HDL-cholesterol), and uric acid among 975 subjects that participated in the health examination of a university hospital located in Daegu city. All the patients' GGT levels were within the normal range. RESULTS: After adjustment were made for age, body mass index (BMI), smoking status, drinking frequency, exercise frequency and coffee intake, the serum GGT level was positively associated with fasting blood glucose (p< 0.01), total cholesterol (p< 0.01), and triglyceride (p< 0.01) in men, and it was positively associated with fasting blood glucose (p< 0.01), total cholesterol (p< 0.05), triglyceride (p< 0.01), and uric acid (p< 0.01) in women. The associations were not significantly different depending on the status of alcohol drinking or obesity, except for the associations of serum GGT with diastolic blood pressure (P for interaction=0.04) and uric acid (P for interaction=0.04) between the lean and obese subjects. CONCLUSIONS: Serum GGT levels within the normal range were positively associated with fasting blood glucose, triglyceride and uric acid in most subgroups irrespective of the drinking or obesity status. These results suggest that GGT has important clinical implications as being more than just a marker of alcohol consumption and hepatobiliary disease.; Summary

Original Articles

Association of Drinking Patterns and Health Characteristics with Beverage Preference.: Jee Jeon Yi, Heechoul Ohrr, Sang Wook Yi, Woo Jin Chung; J Prev Med Public Health. 2004;37(2):133-140.

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Abstract PDF: PURPOSE
To investigate the association between the type of preferred alcoholic beverage and drinking pattern and health characteristics. METHODS: A Cross-sectional study was conducted from 22 April to 3 May in 2002. 301 females and 699 males aged 13 to 59 were personally interviewed. Data on sociodemographic characteristics, drinking pattern and health characteristics were collected. 735 drinkers who were 19 year-old or over were included in analysis. Beverage preference was classified 3 categories: Beer drinker, wine drinker (including wine, makguly, chungju and yakju) and soju drinker (including soju and spirits). RESULTS: Beer drinkers were likely to be females. Compared to wine or soju drinkers, beer drinkers were less frequently drank, and consumed less total alcohol per week and less alcohol per 1 drinking among both male and female. Controlling for various confounders, beer drinker had significantly less total alcohol consumption per week, and alcohol consumption per 1 drinking than wine and soju drinker. CONCLUSION: Beer drinking were associated with less smoking in males and healthy drinking pattern in both gender than soju drinking.; Summary

Association between Alcohol Drinking and Cardiovascular Disease Mortality and All-cause Mortality: Kangwha Cohort Study.: Sang Wook Yi, Sang Hyun Yoo, Jae Woong Sull, Heechoul Ohrr; J Prev Med Public Health. 2004;37(2):120-126.

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Abstract PDF: OBJECTIONS: This study sought to examine relationships between alcohol drinking and cardiovascular disease mortality and all-cause mortality. METHODS: From March 1985 through December 1999, 2, 696 males and 3, 595 females aged 55 or over as of 1985 were followed up for their mortality until 31 December 1999. We calculated the mortality risk ratios by level of alcohol consumption. Among the drinker, the level of alcohol consumption was calculated by the frequency of alcohol comsumption and the type of alcohol. Cox proportional hazard model was used to adjust for confounding factors. RESULTS: Among males, compared to abstainer, heavy drinker had significantly higher mortality in all cause (Risk ratio=1.35), cardiovascular disease (Risk ratio=1.52) and cerebrovascular disease (Risk ratio =1.66). Although not significant, moderate drinker had lower ischemic heart disease mortality (Risk ratio =0.38). Among females, there was no statistically significant association between alcohol comsumption and mortality. CONCLUSION: The results of this study suggest that alcohol drinking has harmful effect on all-cause mortality, cardiovascular disease mortality and cerebrovascular disease mortality among males, especially in heavy drinker among males. Minimal evidence on protective effect for cardiovascular disease mortality in low or moderate drinker is observed.; Summary

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