High Throughput Genotyping for Genomic Cohort Study.

Park, Woong Yang

doi:2007.40.2.102

J Prev Med Public Health > Volume 40(2); 2007 > Article

English Abstract

Journal of Preventive Medicine and Public Health 2007;40(2): 102-107. doi: https://doi.org/10.3961/jpmph.2007.40.2.102

High Throughput Genotyping for Genomic Cohort Study.

Woong Yang Park

Department of Biochemistry and Human Genome Research Institute, Seoul National University College of Medicine, Korea. wypark@snu.ac.kr

ABSTRACT

Human Genome Project (HGP) could unveil the secrets of human being by a long script of genetic codes, which enabled us to get access to mine the cause of diseases more efficiently. Two wheels for HGP, bioinformatics and high throughput technology are essential techniques for the genomic medicine. While microarray platforms are still evolving, we can screen more than 500,000 genotypes at once. Even we can sequence the whole genome of an organism within a day. Because the future medicne will focus on the genetic susceptibility of individuals, we need to find genetic variations of each person by efficient genotyping methods.

Key words: Genotype; Sequence analysis; DNA; Microarray analysis; Single nucleotide polymorphism