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Korean Journal of Preventive Medicine 2002;35(2): 169-174.
A Cross-Sectional Study on gamma-GTP and its Related Factors in Male Workers.
Keon Yeop Kim, Sin Kam, Jong Hyun Lee, Young Ae Ha, Kyung Eun Lee
1Department of Preventive Medicine, School of Medicine, Kyungpook National University, Korea.
2Department of Preventive Medicine, School of Medicine, Ulsan Dong Kang Hospital, Korea.
ABSTRACT
OBJECTIVE: To investigate gamma-Glutamyltransferase (gamma-GTP) and its related factors in male industrial workers. METHOD: Five hundred and forty male workers without heart disease, diabetes mellitus, renal disease, hepatitis, and other liver diseases were surveyed in October 1998. Blood samples were collected to test for gamma-GTP, total-cholesterol and fasting blood glucose. A self-administered questionnaire survey on life style was also done. RESULTS: The total geometric mean value of gamma-GTP was 30.6 U/L. According to a univariate analysis: age, BMI(body mass index, kg/m2), alcohol consumption, current smoking, stress, diastolic blood pressure, and blood total cholesterol were significantly associated with gamma-GTP(p<0.05). From a multiple regression analysis: BMI, alcohol consumption, current smoking, diastolic blood pressure and total-cholesterol were significantly related to gamma-GTP(p<0.05). Coffee consumption was negatively related to gamma-GTP, but not significantly. CONCLUSION: We recommend that a change in health behavior (i.e. reducing alcohol intake, controlling BMI and not smoking) is necessary to decrease gamma-GTP in male workers.
Key words: gamma-Glutamyltransferase; Male
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