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Original Article
- Interaction Between Persistent Organic Pollutants and C-reactive Protein in Estimating Insulin Resistance Among Non-diabetic Adults
- Ki-Su Kim, Nam-Soo Hong, David R Jacobs, Duk-Hee Lee
- J Prev Med Public Health. 2012;45(2):62-69. Published online March 31, 2012
- DOI: https://doi.org/10.3961/jpmph.2012.45.2.62
- 9,888 View
- 81 Download
- 12 Crossref
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Abstract
PDF Objectives Chronic inflammation is now thought to play a key pathogenetic role in the associations of obesity with insulin resistance and diabetes. Based on our recent findings on persistent organic pollutants (POPs) including the lack of an association between obesity and either insulin resistance or diabetes prevalence among subjects with very low concentrations of POPs, we hypothesized that POP concentrations may be associated with inflammation and modify the associations between inflammation and insulin resistance in non-diabetic subjects.
Methods Cross-sectional associations among serum POPs, C-reactive protein (CRP), and homeostasis model assessment of insulin resistance (HOMA-IR) were investigated in 748 non-diabetic participants aged ≥20 years. Nineteen types of POPs in 5 subclasses were selected because the POPs were detectable in ≥60% of the participants.
Results Among the five subclasses of POPs, only organochlorine (OC) pesticides showed positive associations with CRP concentrations, while polychlorinated biphenyls (PCBs) showed inverse associations with CRP concentrations. There were statistically significant interactions between CRP and OC pesticides and between CRP and PCBs, in estimating HOMA-IR (P for interaction <0.01 and <0.01, respectively). CRP was not associated with HOMA-IR among subjects with low concentrations of OC pesticides or PCBs, while CRP was strongly associated with HOMA-IR among subjects with high concentrations of these POPs.
Conclusions In the current study, OC pesticides were associated with increased levels of CRP, a marker of inflammation, and both OC pesticides and PCBs may also modify the associations between CRP and insulin resistance.
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Summary
Citations
Citations to this article as recorded by
- Is Physical Activity an Efficient Strategy to Control the Adverse Effects of Persistent Organic Pollutants in the Context of Obesity? A Narrative Review
Quentin A. Serrano, Sébastien Le Garf, Vincent Martin, Serge S. Colson, Nicolas Chevalier
International Journal of Molecular Sciences.2024; 25(2): 883. CrossRef - The associations between endocrine disrupting chemicals and markers of inflammation and immune responses: A systematic review and meta-analysis
Zhiqin Liu, Yao Lu, Kunxia Zhong, Chenchen Wang, Xi Xu
Ecotoxicology and Environmental Safety.2022; 234: 113382. CrossRef - Endocrine Disruptors and the Induction of Insulin Resistance
Rafael Vanni, Renata Maksoud Bussuan, Renato Luiz Rombaldi, Alberto K. Arbex
Current Diabetes Reviews.2021;[Epub] CrossRef - Influence of polychlorinated biphenyls and organochlorine pesticides on the inflammatory milieu. A systematic review of in vitro, in vivo and epidemiological studies
F.M. Peinado, F. Artacho-Cordón, R. Barrios-Rodríguez, J.P. Arrebola
Environmental Research.2020; 186: 109561. CrossRef - Associations between persistent organic pollutants and metabolic syndrome in morbidly obese individuals
S. Dusanov, J. Ruzzin, H. Kiviranta, T.O. Klemsdal, L. Retterstøl, P. Rantakokko, R. Airaksinen, S. Djurovic, S. Tonstad
Nutrition, Metabolism and Cardiovascular Diseases.2018; 28(7): 735. CrossRef - Health and environmental effects of persistent organic pollutants
Omar M.L. Alharbi, Al Arsh Basheer, Rafat A. Khattab, Imran Ali
Journal of Molecular Liquids.2018; 263: 442. CrossRef - The influence of persistent organic pollutants in the traditional Inuit diet on markers of inflammation
L. K. Schæbel, E. C. Bonefeld-Jørgensen, H. Vestergaard, S. Andersen, Jaymie Meliker
PLOS ONE.2017; 12(5): e0177781. CrossRef - Pesticide Use and Age-Related Macular Degeneration in the Agricultural Health Study
Martha P. Montgomery, Eric Postel, David M. Umbach, Marie Richards, Mary Watson, Aaron Blair, Honglei Chen, Dale P. Sandler, Silke Schmidt, Freya Kamel
Environmental Health Perspectives.2017;[Epub] CrossRef - Hemostatic, inflammatory, and oxidative markers in pesticide user farmers
Fatima Zohra Madani, Merzouk Hafida, Sid Ahmed Merzouk, Bouchra Loukidi, Katia Taouli, Michel Narce
Biomarkers.2016; 21(2): 138. CrossRef - Persistent organic pollutants and biomarkers of diabetes risk in a cohort of Great Lakes sport caught fish consumers
Mary Turyk, Giamila Fantuzzi, Victoria Persky, Sally Freels, Anissa Lambertino, Maria Pini, Davina H. Rhodes, Henry A. Anderson
Environmental Research.2015; 140: 335. CrossRef - Vitamin D-rich marine Inuit diet and markers of inflammation – a population-based survey in Greenland
L. K. Schæbel, E. C. Bonefeld-Jørgensen, P. Laurberg, H. Vestergaard, S. Andersen
Journal of Nutritional Science.2015;[Epub] CrossRef - Persistent Organic Pollutants and Inflammatory Markers in a Cross-Sectional Study of Elderly Swedish People: The PIVUS Cohort
Jitender Kumar, P. Monica Lind, Samira Salihovic, Bert van Bavel, Erik Ingelsson, Lars Lind
Environmental Health Perspectives.2014; 122(9): 977. CrossRef
Research Support, Non-U.S. Gov'ts- The Distribution of Intraocular Pressure and Its Association With Metabolic Syndrome in a Community.
- Sang shin Park, Eun Hee Lee, Ganchimeg Jargal, Domyung Paek, Sung Il Cho
- J Prev Med Public Health. 2010;43(2):125-130.
- DOI: https://doi.org/10.3961/jpmph.2010.43.2.125
- 5,376 View
- 120 Download
- 33 Crossref
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Abstract
PDF
- OBJECTIVES
The current study was performed to assess the distribution of intraocular pressure (IOP) and its association with metabolic syndrome (MS) in a community. METHODS: We measured IOP and MS components from 446 adults, age 20 or more years old, who reside in a community in Kyunggi Province, South Korea. We compared the level of IOP according to the number of metabolic abnormalities and between normal and abnormal metabolic components. Linear regression analyses were used to determine the relationship between IOP and metabolic components. RESULTS: No significant difference in IOP (mean +/- SE) was found between men (12.24 +/- 2.42) and women (12.55 +/- 2.41 mmHg, p > 0.1), while IOP of men tended to decrease as age increased (p for trend < 0.01). After adjusting for age, IOP of subjects with abdominal obesity in men and high blood pressure in women were significantly higher than those without abdominal obesity or high blood pressure (p < 0.05). Female subjects with MS showed significantly higher IOP than those without MS. Participants with more metabolic disturbances tended to have a greater IOP elevation with a linear trend after adjusting for age and sex. In the univariate regression analysis, age and waist circumference were significantly associated with IOP in men, but systolic and diastolic blood pressure were associated with IOP in women. In final multiple regression model, age, systolic blood pressure, and triglyceride were associated with IOP in women, and age in men. CONCLUSIONS: These findings suggest that MS and its components may be important determinants of elevated IOP. -
Summary
Citations
Citations to this article as recorded by- Comparison of Anterior Segment Parameters in Obese Children And Healthy Control Group
Mehmet Tahir ESKİ, Kuddusi TEBERİK, Taha SEZER, İlknur ARSLANOĞLU
Konuralp Tıp Dergisi.2023; 15(2): 190. CrossRef - Prevalence of Ocular Hypertension and Other Risk Factors of Open-Angle Glaucoma Among Middle-Aged Adults in Al-Baha City, Saudi Arabia
Mahadi Bashir, Ali H Alghamdi, Suhaib A Alzahrani, Abdullah M Alhajji, Loay Y Al Thobaiti, Khalid A Alzahrani, Ahmed G Alghamdi, Ranin K Alnemari, Abdulaziz H Althobaiti, Roaa S Alzahrani
Cureus.2023;[Epub] CrossRef - EVALUATION OF THE RELATIONSHIPS BETWEEN OBESITY AND CENTRAL RETINAL THICKNESS, RETINAL NERVE FIBER LAYER, INTRAOCULAR PRESSURE, AND CENTRAL CORNEAL THICKNESS IN CHILDREN
Osman Okan OLCAYSÜ, Buğra KARASU, Elif OLCAYSU, Atilla ÇAYIR, Ali Riza Cenk CELEBİ
Acibadem Universitesi Saglik Bilimleri Dergisi.2022;[Epub] CrossRef - Characterizing the Aging Process of the Human Eye: Tear Evaporation, Fluid Dynamics, Blood Flow, and Metabolism-Based Comparative Study
Md Ashiqur Rahman, Mamun Rabbani, Md Hasan Maruf, Aminul Islam, A. S. M. Shihavuddin, Ali A. Khraibi
BioMed Research International.2022; 2022: 1. CrossRef - Association of Metabolic Syndrome With Glaucoma and Ocular Hypertension in a Midwest United States Population
Kristi Y. Wu, David O. Hodge, Launia J. White, Jacinta McDonald, Gavin W. Roddy
Journal of Glaucoma.2022; 31(6): e18. CrossRef - The Impact of Systemic Health Parameters on Intraocular Pressure in the Western Region of Saudi Arabia
Nawaf Almarzouki, Sumayya A Bafail , Daniyah H Danish, Sultan R Algethami, Noorah Shikdar, Saif Ashram, Tala Roblah
Cureus.2022;[Epub] CrossRef - The Association Between Age and Systemic Variables and the Longitudinal Trend of Intraocular Pressure in a Large-Scale Health Examination Cohort
Ryo Asaoka, Akira Obana, Hiroshi Murata, Yuri Fujino, Takashi Omoto, Shuichiro Aoki, Shigetaka Muto, Yuji Takayanagi, Tatsuya Inoue, Masaki Tanito
Investigative Opthalmology & Visual Science.2022; 63(11): 22. CrossRef - Age-Related Changes in Intraocular Pressure: Japan Ningen Dock Study
Ryo Terauchi, Takashi Wada, Kota Fukai, Masayuki Tatemichi, Shumpei Ogawa, Takahiko Noro, Kyoko Ito, Tomohiro Kato, Kiminori Kato, Tadashi Nakano
Journal of Glaucoma.2022; 31(12): 927. CrossRef - Effects of French maritime pine bark/bilberry fruit extracts on intraocular pressure for primary open-angle glaucoma
Kaoru Manabe, Sachiko Kaidzu, Aika Tsutsui, Mihoko Mochiji, Yotaro Matsuoka, Yasutaka Takagi, Etsuyo Miyamoto, Masaki Tanito
Journal of Clinical Biochemistry and Nutrition.2021; 68(1): 67. CrossRef - Predicting intraocular pressure using systemic variables or fundus photography with deep learning in a health examination cohort
Kaori Ishii, Ryo Asaoka, Takashi Omoto, Shingo Mitaki, Yuri Fujino, Hiroshi Murata, Keiichi Onoda, Atsushi Nagai, Shuhei Yamaguchi, Akira Obana, Masaki Tanito
Scientific Reports.2021;[Epub] CrossRef - Metabolic syndrome and the aging retina
Gavin W. Roddy
Current Opinion in Ophthalmology.2021; 32(3): 280. CrossRef - Obesity, Blood Pressure, and Intraocular Pressure: A Cross-Sectional Study in Italian Children
Claudia Pileggi, Rosa Papadopoli, Caterina De Sarro, Carmelo Giuseppe Angelo Nobile, Maria Pavia
Obesity Facts.2021; 14(2): 169. CrossRef - Systemic factors associated with intraocular pressure among subjects in a health examination program in Japan
Satsuki Takahashi, Katsunori Hara, Ichiya Sano, Keiichi Onoda, Atsushi Nagai, Shuhei Yamaguchi, Masaki Tanito, Der-Chong Tsai
PLOS ONE.2020; 15(6): e0234042. CrossRef - The Association between Metabolic Abnormalities and Ocular Perfusion Pressure in Healthy Korean Adults
Jeong Min Kwon, Jonghoon Shin
Journal of the Korean Glaucoma Society.2020; 9(1): 17. CrossRef - Metabolic Syndrome Is Associated With Ocular Hypertension and Glaucoma
Gavin W. Roddy
Journal of Glaucoma.2020; 29(9): 726. CrossRef - Heterogeneity in arterial hypertension and ocular perfusion pressure definitions: Towards a consensus on blood pressure‐related parameters for glaucoma studies
João Barbosa‐Breda, Luis Abegão‐Pinto, Karel Van Keer, Danilo A. Jesus, Sophie Lemmens, Evelien Vandewalle, Amândio Rocha‐Sousa, Ingeborg Stalmans
Acta Ophthalmologica.2019;[Epub] CrossRef - Gender Difference in Intraocular Pressure and Incidence of Metabolic Syndrome: A Community-Based Cohort Study in Matsu, Taiwan
Raymond N. Kuo, Chia-Ching Yang, Amy Ming-Fang Yen, Tzeng-Ying Liu, Ming-Wei Lin, Sam Li-Sheng Chen
Metabolic Syndrome and Related Disorders.2019; 17(6): 334. CrossRef - Distribution of IOP measured with an air puff tonometer in a young population
Hassan Hashemi, Mehdi Khabazkhoob, Payam Nabovati, Negareh Yazdani, Hadi Ostadimoghaddam, Ehsan Shiralivand, Akbar Derakhshan, AbbasAli Yekta
Journal of Current Ophthalmology.2018; 30(1): 35. CrossRef - Relationship Between Serum Glucose Levels and Intraocular Pressure, a Population-based Cross-sectional Study
Eytan Cohen, Michal Kramer, Tzippy Shochat, Elad Goldberg, Ilan Krause
Journal of Glaucoma.2017; 26(7): 652. CrossRef - The synergistic effect of inflammation and metabolic syndrome on intraocular pressure
I-Te Lee, Jun-Sing Wang, Chia-Po Fu, Chia-Jen Chang, Wen-Jane Lee, Shih-Yi Lin, Wayne Huey-Herng Sheu
Medicine.2017; 96(36): e7851. CrossRef - The association between intraocular pressure and different combination of metabolic syndrome components
JunSeok Son, HyunMin Koh, JunHyuk Son
BMC Ophthalmology.2016;[Epub] CrossRef - Evaluation of the associations between changes in intraocular pressure and metabolic syndrome parameters: a retrospective cohort study in Japan
Hiroshi Yokomichi, Kenji Kashiwagi, Kazuyoshi Kitamura, Yoshioki Yoda, Masahiro Tsuji, Mie Mochizuki, Miri Sato, Ryoji Shinohara, Sonoko Mizorogi, Kohta Suzuki, Zentaro Yamagata
BMJ Open.2016; 6(3): e010360. CrossRef - Associations of blood heavy metal levels with intraocular pressure
Sangshin Park, Nam-Kyong Choi
Annals of Epidemiology.2016; 26(8): 546. CrossRef - A Longitudinal Study of Association between Adiposity Markers and Intraocular Pressure: The Kangbuk Samsung Health Study
Di Zhao, Myung Hun Kim, Roberto Pastor-Barriuso, Yoosoo Chang, Seungho Ryu, Yiyi Zhang, Sanjay Rampal, Hocheol Shin, Joon Mo Kim, David S. Friedman, Eliseo Guallar, Juhee Cho, Demetrios Vavvas
PLOS ONE.2016; 11(1): e0146057. CrossRef - Relationship Between Intraocular Pressure and Parameters of Obesity in Korean Adults: The 2008–2010 Korea National Health and Nutrition Examination Survey
Hyung-Deok Jang, Do Hoon Kim, Kyungdo Han, Suk Gyu Ha, Yang Hyun Kim, Jae Woo Kim, Ji Young Park, Su Jung Yoon, Dong Wook Jung, Sang Woon Park, Ga Eun Nam
Current Eye Research.2015; 40(10): 1008. CrossRef - The Association between Primary Open-Angle Glaucoma and Blood Pressure: Two Aspects of Hypertension and Hypotension
Hye Jin Chung, Hyung Bin Hwang, Na Young Lee
BioMed Research International.2015; 2015: 1. CrossRef - Association of IOP with Systemic Factors in a Korean Cohort
Yang Jae Kim, Yeoun Sook Chun, Mi Yeon Lee, Joon Mo Kim, Seong Hee Shim, Chungkwon Yoo, Jeong Hun Bae, Ki Ho Park
Optometry and Vision Science.2015; 92(12): 1182. CrossRef - The Association of Blood Pressure and Primary Open-Angle Glaucoma: A Meta-analysis
Di Zhao, Juhee Cho, Myung Hun Kim, Eliseo Guallar
American Journal of Ophthalmology.2014; 158(3): 615. CrossRef - High intraocular pressure is associated with cardiometabolic risk factors in South Korean men: Korean National Health and Nutrition Examination Survey, 2008–2010
Y-H Kim, S W Jung, G-E Nam, K Do Han, A R Bok, S J Baek, K-H Cho, Y S Choi, S-M Kim, S-Y Ju, D-H Kim
Eye.2014; 28(6): 672. CrossRef - Diabetes, Glucose Metabolism, and Glaucoma: The 2005–2008 National Health and Nutrition Examination Survey
Di Zhao, Juhee Cho, Myung Hun Kim, David Friedman, Eliseo Guallar, Sanjoy Bhattacharya
PLoS ONE.2014; 9(11): e112460. CrossRef - Distribution of Intraocular Pressure and Its Association with Ocular Features and Cardiovascular Risk Factors
René Hoehn, Alireza Mirshahi, Esther M. Hoffmann, Ulrike B. Kottler, Philipp S. Wild, Dagmar Laubert-Reh, Norbert Pfeiffer
Ophthalmology.2013; 120(5): 961. CrossRef - Epidemiologic Characteristics of Intraocular Pressure in the Korean and Mongolian Populations: The Healthy Twin and the GENDISCAN Study
Mi Kyeong Lee, Sung-Il Cho, Ho Kim, Yun-Mi Song, Kayoung Lee, Jong-Il Kim, Dong-Myung Kim, Tae-Young Chung, Youn Sic Kim, Jeong-Sun Seo, Don-Il Ham, Joohon Sung
Ophthalmology.2012; 119(3): 450. CrossRef - Age- and gender-specific association between intraocular pressure and metabolic variables in a Taiwanese population
Chia-Pin Lin, Yu-Sheng Lin, Shiu-Chen Wu, Yu-Shien Ko
European Journal of Internal Medicine.2012; 23(1): 76. CrossRef
- Relationship Between Serum Concentrations of Organochlorine Pesticides and Metabolic Syndrome Among Non-Diabetic Adults.
- Sun Kyun Park, Hyo Kyung Son, Sung Kook Lee, Jung Ho Kang, Yoon Seok Chang, David R Jacobs, Duk Hee Lee
- J Prev Med Public Health. 2010;43(1):1-8.
- DOI: https://doi.org/10.3961/jpmph.2010.43.1.1
- 5,722 View
- 131 Download
- 42 Crossref
-
Abstract
PDF
- OBJECTIVES
This study was performed to investigate if organochlorine pesticides (OCPs) were associated with metabolic syndrome and insulin resistance among non-diabetes. METHODS: Among subjects who participated in a community-based health survey, 50 non-diabetic subjects with metabolic syndrome and 50 normal controls were selected. Insulin resistance was measured by the homeostasis model assessment (HOMA-IR). Eight OCPs were selected. RESULTS: After adjusting for confounders except for body mass index (BMI), beta-hexachlorocyclohexane (beta-HCH) and heptachlor epoxide were positively associated with metabolic syndrome. Odds ratios across tertiles of beta-HCH and heptachlor epoxide were 1.0, 3.2 and 4.4, and 1.0, 4.0 and 6.0, respectively (p for trend = 0.01 and <0.01). After additional adjustment for body mass index (BMI), heptachlor epoxide still showed an increasing trend with adjusted odds ratios of 1.0, 4.1, and 4.6 (p for trend = 0.10). When the five components of metabolic syndrome (with the definition of high fasting glucose (> or =100 mg/dL)) were separately analyzed, all components were positively, but not significantly, associated with heptachlor epoxide. As the serum concentration of heptachlor epoxide increased, HOMA-IR increased significantly in subjects with metabolic syndrome even after adjusting for BMI (p value <0.05 and <0.01). CONCLUSIONS: Despite the small sample size, this study suggests that the background exposure to some OCPs may be associated with metabolic syndrome. -
Summary
Citations
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Jian-Yan Lin, Rui-Xing Yin
Exposure and Health.2023; 15(1): 199. CrossRef - Cross-sectional associations of persistent organic pollutants measured in adipose tissue and metabolic syndrome in clinically diagnosed middle-aged adults
Iris Reina-Pérez, Francisco Artacho-Cordón, Vicente Mustieles, Daniel Castellano-Castillo, Fernando Cardona, Inmaculada Jiménez-Díaz, Jose A. López-Medina, Juan Alcaide, Luis Ocaña-Wilhelmi, Luz M. Iribarne-Durán, Juan P. Arrebola, Nicolás Olea, Francisco
Environmental Research.2023; 222: 115350. CrossRef - Effect of persistent organic pollutants in patients with ischemic stroke and all stroke: A systematic review and meta-analysis
Priya Dev, Kamalesh Chakravarty, Manoj Pandey, Rakesh Ranjan, Mareena Cyriac, Vijaya Nath Mishra, Abhishek Pathak
Toxicology.2023; 494: 153567. CrossRef - Pesticides and insulin resistance-related metabolic diseases: Evidences and mechanisms
Ali Arab, Sara Mostafalou
Pesticide Biochemistry and Physiology.2023; 195: 105521. CrossRef - Health risk assessment of exposure to organochlorine pesticides in the general population in Seoul, Korea over 12 years: A cross-sectional epidemiological study
Sung-Hee Seo, Sung-Deuk Choi, Stuart Batterman, Yoon-Seok Chang
Journal of Hazardous Materials.2022; 424: 127381. CrossRef - Differential Bioaccumulation Patterns of α, β-Hexachlorobenzene and Dicofol in Adipose Tissue from the GraMo Cohort (Southern Spain)
Inmaculada Salcedo-Bellido, Esperanza Amaya, Celia Pérez-Díaz, Anabel Soler, Fernando Vela-Soria, Pilar Requena, Rocío Barrios-Rodríguez, Ruth Echeverría, Francisco M. Pérez-Carrascosa, Raquel Quesada-Jiménez, Piedad Martín-Olmedo, Juan Pedro Arrebola
International Journal of Environmental Research and Public Health.2022; 19(6): 3344. CrossRef - Association of Organochlorine Pesticides With Genetic Markers of Endoplasmic Reticulum Stress in Type 2 Diabetes Mellitus: A Case–Control Study Among the North-Indian Population
Neha Tawar, Basu Dev Banerjee, Sri Venkata Madhu, Vivek Agrawal, Sanjay Gupta
Frontiers in Endocrinology.2022;[Epub] CrossRef - Environmental Chemical Contribution to the Modulation of Bile Acid Homeostasis and Farnesoid X Receptor Signaling
Rulaiha E. Taylor, Anisha Bhattacharya, Grace L. Guo
Drug Metabolism and Disposition.2022; 50(4): 456. CrossRef - Metabolic syndrome and pesticides: A systematic review and meta-analysis
Hugo Lamat, Marie-Pierre Sauvant-Rochat, Igor Tauveron, Reza Bagheri, Ukadike C. Ugbolue, Salwan Maqdasi, Valentin Navel, Frédéric Dutheil
Environmental Pollution.2022; 305: 119288. CrossRef - Impact of Chemical Endocrine Disruptors and Hormone Modulators on the Endocrine System
Valentina Guarnotta, Roberta Amodei, Francesco Frasca, Antonio Aversa, Carla Giordano
International Journal of Molecular Sciences.2022; 23(10): 5710. CrossRef - Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors
Kévin Bernal, Charbel Touma, Chedi Erradhouani, Talía Boronat‐Belda, Lucas Gaillard, Sara Al Kassir, Hélène Le Mentec, Corinne Martin‐Chouly, Normand Podechard, Dominique Lagadic‐Gossmann, Sophie Langouet, François Brion, Anja Knoll‐Gellida, Patrick J. Ba
FEBS Letters.2022; 596(24): 3107. CrossRef - Gene expression in rat placenta after exposure to di(2-ethylhexyl) phthalate
Wan Xu, Hongyan Wu, Lixin Shang
Human & Experimental Toxicology.2021; 40(3): 504. CrossRef - Umweltgifte und ihre hormonelle Wirkung
Roxana M. Popovici, Barbara Sonntag
Der Gynäkologe.2021; 54(4): 246. CrossRef - The association between environmental exposures to chlordanes, adiposity and diabetes-related features: a systematic review and meta-analysis
Vânia Mendes, Cláudia Ribeiro, Inês Delgado, Bárbara Peleteiro, Martine Aggerbeck, Emilie Distel, Isabella Annesi-Maesano, Denis Sarigiannis, Elisabete Ramos
Scientific Reports.2021;[Epub] CrossRef - Metabolic Syndrome and Endocrine Disrupting Chemicals: An Overview of Exposure and Health Effects
Elsi Haverinen, Mariana F. Fernandez, Vicente Mustieles, Hanna Tolonen
International Journal of Environmental Research and Public Health.2021; 18(24): 13047. CrossRef - Smokeless tobacco use: its prevalence and relationships with dental symptoms, nutritional status and blood pressure among rural women in Burkina Faso
Jeoffray Diendéré, Augustin Nawidimbasba Zeba, Léon Nikièma, Ahmed Kaboré, Paul Windinpsidi Savadogo, Somnoma Jean-Baptiste Tougma, Halidou Tinto, Arouna Ouédraogo
BMC Public Health.2020;[Epub] CrossRef - Persistent Organic Pollutant-Mediated Insulin Resistance
Yeon Kim, Joon Park, Min Woo, Sang Lee, Hye Kim, Young Yoo
International Journal of Environmental Research and Public Health.2019; 16(3): 448. CrossRef - Blood Concentrations of Persistent Organic Pollutants and Unhealthy Metabolic Phenotypes in Normal-Weight, Overweight, and Obese Individuals
Magda Gasull, Conxa Castell, Natàlia Pallarès, Carme Miret, José Pumarega, María Téllez-Plaza, Tomàs López, Jordi Salas-Salvadó, Duk-Hee Lee, Albert Goday, Miquel Porta
American Journal of Epidemiology.2018; 187(3): 494. CrossRef - “Trans-nonachlor increases extracellular free fatty acid accumulation and de novo lipogenesis to produce hepatic steatosis in McArdle-RH7777 cells”
George Eli Howell, Erin McDevitt, Lucie Henein, Charlee Mulligan, Darian Young
Toxicology in Vitro.2018; 50: 285. CrossRef - Effects on the reproductive parameters of two generations ofRattus norvegicusoffspring from dams exposed to heptachlor during gestation and lactation
Alejandra Martínez-Ibarra, Sumiko Morimoto, Marco Cerbón, Guadalupe Prado-Flores
Environmental Toxicology.2017; 32(3): 856. CrossRef - Exposure to an environmentally relevant mixture of organochlorine compounds and polychlorinated biphenyls Promotes hepatic steatosis in male Ob/Ob mice
Charlee Mulligan, Sandeep Kondakala, Eun‐Ju Yang, John V. Stokes, James A. Stewart, Barbara L. F. Kaplan, George E. Howell
Environmental Toxicology.2017; 32(4): 1399. CrossRef - Mixture effects of 30 environmental contaminants on incident metabolic syndrome—A prospective study
Lars Lind, Samira Salihovic, Erik Lampa, P. Monica Lind
Environment International.2017; 107: 8. CrossRef - Human adipose tissue levels of persistent organic pollutants and metabolic syndrome components: Combining a cross-sectional with a 10-year longitudinal study using a multi-pollutant approach
Vicente Mustieles, Mariana F. Fernández, Piedad Martin-Olmedo, Beatriz González-Alzaga, Andrés Fontalba-Navas, Russ Hauser, Nicolás Olea, Juan P. Arrebola
Environment International.2017; 104: 48. CrossRef - Metabolic syndrome is associated with exposure to organochlorine pesticides in Anniston, AL, United States
Paula F. Rosenbaum, Ruth S. Weinstock, Allen E. Silverstone, Andreas Sjödin, Marian Pavuk
Environment International.2017; 108: 11. CrossRef - Endocrine‐disrupting chemicals, risk of type 2 diabetes, and diabetes‐related metabolic traits: A systematic review and meta‐analysis
Yan Song, Elizabeth L. Chou, Aileen Baecker, Nai‐Chieh Y. You, Yiqing Song, Qi Sun, Simin Liu
Journal of Diabetes.2016; 8(4): 516. CrossRef - Article Commentary: Effects of Environmental Pollutants on Cellular Iron Homeostasis and Ultimate Links to Human Disease
Dina M. Schreinemachers, Andrew J. Ghio
Environmental Health Insights.2016; 10: EHI.S36225. CrossRef - Persistent organic pollutants and promoter hypermethylation of the O6-methylguanine-DNA methyltransferase gene
Soo Yeun Park, Ki-Su Kim, Yu-Mi Lee, Mi-Jin Kim, David R. Jacobs, Miquel Porta, Dong-Sun Kim, Duk-Hee Lee
Biomarkers.2015; 20(2): 136. CrossRef - Association of persistent organic pollutants and non-persistent pesticides with diabetes and diabetes-related health outcomes in Asia: A systematic review
Lindsay M. Jaacks, Lisa R. Staimez
Environment International.2015; 76: 57. CrossRef - Endokrin wirkende Umweltgifte
Roxana M. Popovici
Gynäkologische Endokrinologie.2015; 13(3): 168. CrossRef - Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites
Nora Klöting, Nico Hesselbarth, Martin Gericke, Anne Kunath, Ronald Biemann, Rima Chakaroun, Joanna Kosacka, Peter Kovacs, Matthias Kern, Michael Stumvoll, Bernd Fischer, Ulrike Rolle-Kampczyk, Ralph Feltens, Wolfgang Otto, Dirk K. Wissenbach, Martin von
PLOS ONE.2015; 10(12): e0143190. CrossRef - Umweltgifte und ihre hormonelle Wirkung
R.M. Popovici
Humanmedizin kompakt.2014;[Epub] CrossRef - Prospective associations between persistent organic pollutants and metabolic syndrome: A nested case–control study
Yu-Mi Lee, Ki-Su Kim, Se-A Kim, Nam-Soo Hong, Su-Jin Lee, Duk-Hee Lee
Science of The Total Environment.2014; 496: 219. CrossRef - Association of Persistent Organic Pollutants (POPs) with Age and Body Mass Index in Korean Adults
Ho Jung Moon, Jung-Eun Lim, Sun Ha Jee
Korean Journal of Environmental Health Sciences.2014; 40(6): 442. CrossRef - Perinatal Exposure to Low-Dose Methoxychlor Impairs Testicular Development in C57BL/6 Mice
Xiaohong Du, Hua Zhang, Yuanwu Liu, Wanpeng Yu, Chaobin Huang, Xiangdong Li, Stefan Schlatt
PLoS ONE.2014; 9(7): e103016. CrossRef - TCDD-Elicited Effects on Liver, Serum, and Adipose Lipid Composition in C57BL/6 Mice
Michelle Manente Angrish, Claudia Yvette Dominici, Timothy Richard Zacharewski
Toxicological Sciences.2013; 131(1): 108. CrossRef - Developmental origins of obesity and type 2 diabetes: molecular aspects and role of chemicals
Hidekuni Inadera
Environmental Health and Preventive Medicine.2013; 18(3): 185. CrossRef - Agricultural Exposures and Stroke Mortality in the Agricultural Health Study
Jessica L. Rinsky, Jane A. Hoppin, Aaron Blair, Ka He, Laura E. Beane Freeman, Honglei Chen
Journal of Toxicology and Environmental Health, Part A.2013; 76(13): 798. CrossRef - Umweltgifte und ihre hormonelle Wirkung
R.M. Popovici
Gynäkologische Endokrinologie.2013; 11(3): 213. CrossRef - Can persistent organic pollutants and plastic‐associated chemicals cause cardiovascular disease?
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English Abstract- Associations of Non Alcoholic Fatty Liver with the Metabolic Syndrome and Serum Carotenoids.
- Sun kyun Park, Hyun Jung Lee, Duk Hee Lee, Sung Kook Lee, Byung Yeol Chun, Sung Ae Kim, Hye Sung Lee, Hyo Kyung Son, Sung Hi Kim
- J Prev Med Public Health. 2008;41(1):39-44.
- DOI: https://doi.org/10.3961/jpmph.2008.41.1.39
- 5,556 View
- 66 Download
- 9 Crossref
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Abstract
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- OBJECTIVES
This study was conducted to investigate the associations of non alcoholic fatty liver with metabolic syndrome and the serum carotenoids. METHODS: This study was conducted in a general hospital in South Korea from November, 2004 to August, 2005. The study subjects were 350 sampled persons who were aged from 40 years and older (males: 180, females: 170). They were grouped into the normal, mild and severe groups according to fat accumulation in their livers, as determined by ultrasonography. We analyzed the association between non alcoholic fatty liver and metabolic syndrome by multiple logistic regression analysis and we analyzed the association between non alcoholic fatty liver and the serum carotenoids by a general linear model(ANCOVA). RESULTS: After adjustment for the effect of potential covariates, the prevalence of metabolic syndrome was associated with fat accumulation in the liver (p trend <0.001). If the odds ratio of normal group is 1.00, then that of the mild group is 2.80 (95% C.I=1.17-6.71) and that of the severe group is 7.29 (95% C.I=2.76-19.30). The prevalence of metabolic alterations fitting the criteria of metabolic syndrome, according to the class of fat accumulation in the liver, was significantly increased, except for criteria of high blood pressure, a large waist circumference and low HDL (high density lipoprotein) cholesterol level (p trend <0.001). The level of serum beta-carotene was decreased according to the class of fat accumulation in the liver (p trend=0.036), but the levels of serum alpha-carotene, lycopene, bata-cryptoxanthin and lutein were not decreased. CONCLSIONS: This study shows that non alcoholic fatty liver was associated with metabolic syndrome and with the serum beta-carotene level. -
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Citations
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