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HOME > Korean J Prev Med > Volume 24(1); 1991 > Article
Original Article Serum protein concentrations and electrophoretic patterns by categories of small opacity profusions in coal workers' pneumoconioses.
Jeong Pyo Hong, Ho Keun Chung
Journal of Preventive Medicine and Public Health 1991;24(1):1-7
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Institute of Occupational Diseases Korea Labour Welfare Corporation, Korea.

The concentrations of serum proteins fractions and their electrophoretical patterns were investigated in 135 patients with coal workers' pneumoconiosis who participated in confirmative examination for pneumoconiosis in December 1989. Their radiographical profusions were classified as 1/0 or more. Agarose film and phosphoric acid-sodium hydroxide buffer(pH 8.6) were used for electrophoresis. Concentration of each protein fractions and electrophoretical patterns seemed to be equivalent to reference values. Serum alpah1- and beta-globulin concentrations, however, were significantly different(p<0.50) among categories of small opacity profusions and showed the lowest level in the group of category 1. Albumin concentrations decreased and alpha2-globulin concentrations increased significantly(p<0.05) in the group of complicated with pulmonary tuberculosis. gamma-globulin concentrations were not varied by category of profusions nor by pulmonary tuberculosis complication.

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JPMPH : Journal of Preventive Medicine and Public Health