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Hye-Young Seo 4 Articles
Metabolic Risk Profile and Cancer in Korean Men and Women
Seulki Ko, Seok-Jun Yoon, Dongwoo Kim, A-Rim Kim, Eun-Jung Kim, Hye-Young Seo
J Prev Med Public Health. 2016;49(3):143-152.   Published online May 18, 2016
DOI: https://doi.org/10.3961/jpmph.16.021
  • 11,100 View
  • 285 Download
  • 35 Crossref
AbstractAbstract PDF
Objectives
Metabolic syndrome is a cluster of risk factors for type 2 diabetes mellitus and cardiovascular disease. Associations between metabolic syndrome and several types of cancer have recently been documented.
Methods
We analyzed the sample cohort data from the Korean National Health Insurance Service from 2002, with a follow-up period extending to 2013. The cohort data included 99 565 individuals who participated in the health examination program and whose data were therefore present in the cohort database. The metabolic risk profile of each participant was assessed based on obesity, high serum glucose and total cholesterol levels, and high blood pressure. The occurrence of cancer was identified using Korean National Health Insurance claims data. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards models, adjusting for age group, smoking status, alcohol intake, and regular exercise.
Results
A total of 5937 cases of cancer occurred during a mean follow-up period of 10.4 years. In men with a high-risk metabolic profile, the risk of colon cancer was elevated (HR, 1.40; 95% CI, 1.14 to 1.71). In women, a high-risk metabolic profile was associated with a significantly increased risk of gallbladder and biliary tract cancer (HR, 2.05; 95% CI, 1.24 to 3.42). Non-significantly increased risks were observed in men for pharynx, larynx, rectum, and kidney cancer, and in women for colon, liver, breast, and ovarian cancer.
Conclusions
The findings of this study support the previously suggested association between metabolic syndrome and the risk of several cancers. A high-risk metabolic profile may be an important risk factor for colon cancer in Korean men and gallbladder and biliary tract cancer in Korean women.
Summary

Citations

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    Jingxuan Liu, Rui Wang, Song Tan, Xiaohu Zhao, Aihua Hou
    Diabetology & Metabolic Syndrome.2024;[Epub]     CrossRef
  • Metabolic syndrome and risk of ovarian cancer: a systematic review and meta-analysis
    Ziyu Chen, Zesi Liu, Hongxia Yang, Chaosheng Liu, Fandou Kong
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
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    Junjie Huang, Don Eliseo Lucero-Prisno, Lin Zhang, Wanghong Xu, Sunny H. Wong, Siew C. Ng, Martin C. S. Wong
    Nature Reviews Gastroenterology & Hepatology.2023; 20(5): 271.     CrossRef
  • Association of metabolic syndrome and its components with the risk of kidney cancer: A cohort-based case-control study
    Runxue Jiang, Zhi Li, Xia Wang, Haifeng Cai, Shouling Wu, Shuohua Chen, Hailong Hu
    Technology and Health Care.2023; 31(4): 1235.     CrossRef
  • Association between metabolic syndrome and gastric cancer risk: results from the Health Examinees Study
    Dan Huang, Woo-Kyoung Shin, Katherine De la Torre, Hwi-Won Lee, Sukhong Min, Aesun Shin, Jong-Koo Lee, Daehee Kang
    Gastric Cancer.2023; 26(4): 481.     CrossRef
  • Association Between Metabolic Syndrome and the Risk of Lung Cancer: A Meta-Analysis
    Zhao Zhang, Qinxiang Liu, Congcong Huang, Jun Wu, Yingsheng Wen
    Hormone and Metabolic Research.2023; 55(12): 846.     CrossRef
  • The association between metabolic risk factors, nonalcoholic fatty liver disease, and the incidence of liver cancer: a nationwide population-based cohort study
    Yu-Guang Chen, Chih-Wei Yang, Chi-Hsiang Chung, Ching-Liang Ho, Wei-Liang Chen, Wu-Chien Chien
    Hepatology International.2022; 16(4): 807.     CrossRef
  • The Importance of Metabolic Syndrome Status for the Risk of Non-Viral Hepatocellular Carcinoma: A Nationwide Population-Based Study
    Yuri Cho, Eun Ju Cho, Jeong-Ju Yoo, Young Chang, Goh Eun Chung, In Young Choi, Sang-Hyun Park, Kyungdo Han, Yoon Jun Kim, Jung-Hwan Yoon, Dong Wook Shin, Su Jong Yu
    Frontiers in Oncology.2022;[Epub]     CrossRef
  • Association of Hypertension and Organ-Specific Cancer: A Meta-Analysis
    Morgan Connaughton, Mahsa Dabagh
    Healthcare.2022; 10(6): 1074.     CrossRef
  • Association Between Metabolic Syndrome and Risk of Renal Cell Cancer: A Meta-Analysis
    Wurong Du, Kaibo Guo, Huimin Jin, Leitao Sun, Shanming Ruan, Qiaoling Song
    Frontiers in Oncology.2022;[Epub]     CrossRef
  • The Association Between Metabolic Syndrome and Colorectal Cancer Risk by Obesity Status in Korean Women: A Nationwide Cohort Study
    Seong-geun Moon, Boyoung Park
    Journal of Preventive Medicine and Public Health.2022; 55(5): 475.     CrossRef
  • The association between hypertension and colorectal cancer: a meta-analysis of observational studies
    Kun Xuan, Tianming Zhao, Chenyu Sun, Akash S. Patel, Haixia Liu, Xin Chen, Guangbo Qu, Yehuan Sun
    European Journal of Cancer Prevention.2021; 30(1): 84.     CrossRef
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    Jinjia Zhang, Huadong Wu, Rongying Wang
    Diabetology & Metabolic Syndrome.2021;[Epub]     CrossRef
  • Metabolic syndrome and gastric cancer risk: a systematic review and meta-analysis
    Marco Mariani, Michele Sassano, Stefania Boccia
    European Journal of Cancer Prevention.2021; 30(3): 239.     CrossRef
  • Persistent status of metabolic syndrome and risk of cholangiocarcinoma: A Korean nationwide population-based cohort study
    Joo-Hyun Park, Jung Y. Hong, Young S. Park, Gunseog Kang, Kyungdo Han, Joon O. Park
    European Journal of Cancer.2021; 155: 97.     CrossRef
  • Metabolic syndrome and the risk of colorectal cancer: a systematic review and meta-analysis
    Xiaoding Shen, Yong Wang, Rui Zhao, Qianyi Wan, Yutao Wu, Lihao Zhao, Xiaoting Wu
    International Journal of Colorectal Disease.2021; 36(10): 2215.     CrossRef
  • Metabolic syndrome and its component traits present gender-specific association with liver cancer risk: a prospective cohort study
    Bin Xia, Jianjun Peng, De Toni Enrico, Kuiqing Lu, Eddie C. Cheung, Zichong Kuo, Qiangsheng He, Yan Tang, Anran Liu, Die Fan, Changhua Zhang, Yulong He, Yihang Pan, Jinqiu Yuan
    BMC Cancer.2021;[Epub]     CrossRef
  • Association between Abdominal Obesity and Incident Colorectal Cancer: A Nationwide Cohort Study in Korea
    Ga Eun Nam, Se-Jin Baek, Hong Bae Choi, Kyungdo Han, Jung-Myun Kwak, Jin Kim, Seon-Hahn Kim
    Cancers.2020; 12(6): 1368.     CrossRef
  • Metabolic Syndrome and Risk of Lung Cancer: An Analysis of Korean National Health Insurance Corporation Database
    Sooim Sin, Chang-Hoon Lee, Sun Mi Choi, Kyung-Do Han, Jinwoo Lee
    The Journal of Clinical Endocrinology & Metabolism.2020; 105(11): e4102.     CrossRef
  • Metabolic syndrome and the incidence of lung cancer: a meta-analysis of cohort studies
    Li Qiao, Deliang Ma, Hui Lv, Ding Shi, Min Fei, Yu Chen, Fei Xie, Zhuoyan Wang, Ying Wang, Wanhua Liang, Peiying Hu
    Diabetology & Metabolic Syndrome.2020;[Epub]     CrossRef
  • Metabolic Syndrome and Colorectal Cancer Risk: Results of Propensity Score-Based Analyses in a Community-Based Cohort Study
    Jinsun Kim, Eun Young Park, Eunjung Park, Min Kyung Lim, Jin-Kyoung Oh, Byungmi Kim
    International Journal of Environmental Research and Public Health.2020; 17(22): 8687.     CrossRef
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    Ping Zhao, Ning Xia, Hong Zhang, Tingting Deng
    Obesity Facts.2020; 13(4): 384.     CrossRef
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    Huina Ren, Junna Wang, Yue Gao, Fuwei Yang, Wenxiang Huang
    BMC Endocrine Disorders.2019;[Epub]     CrossRef
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    Aristeidis Seretis, Sofia Cividini, Georgios Markozannes, Xanthippi Tseretopoulou, David S. Lopez, Evangelia E. Ntzani, Konstantinos K. Tsilidis
    Scientific Reports.2019;[Epub]     CrossRef
  • Metabolic syndrome and risk of ovarian and fallopian tube cancer in the United States: An analysis of linked SEER–Medicare data
    Kara A. Michels, Timothy S. McNeel, Britton Trabert
    Gynecologic Oncology.2019; 155(2): 294.     CrossRef
  • Association between metabolic syndrome and the incidence of gastric cancer: a meta-analysis of cohort studies
    Zhibin Li, Hongfeng Han, Yuan Chang
    Diabetology & Metabolic Syndrome.2019;[Epub]     CrossRef
  • Association Between Metabolic Syndrome and Breast Cancer Risk: An Updated Meta-Analysis of Follow-Up Studies
    Meng Guo, Tingting Liu, Peiting Li, Tianying Wang, Chen Zeng, Meng Yang, Gang Li, Jiang Han, Wei Wu, Ruopeng Zhang
    Frontiers in Oncology.2019;[Epub]     CrossRef
  • Incidence of Colon Cancer Related to Cigarette Smoking and Alcohol Consumption in Adults with Metabolic Syndrome: Prospective Cohort Study
    Ahra Jo, Heeyoung Oh
    Journal of Korean Academy of Nursing.2019; 49(6): 713.     CrossRef
  • Molecular targets for the therapy of cancer associated with metabolic syndrome (transcription and growth factors)
    Natalia V. Yunusova, Irina V. Kondakova, Larisa A. Kolomiets, Sergey G. Afanas'ev, Alena L. Chernyshova, Igor V. Kudryavtsev, Anastasia A. Tsydenova
    Asia-Pacific Journal of Clinical Oncology.2018; 14(3): 134.     CrossRef
  • Incidence and risk factors of colorectal cancer based on 56 324 health checkups: A 7‐year retrospective cohort study
    Toshiko Fujii, Masayuki Ohisa, Toru Sako, Takayuki Harakawa, Kazuaki Sakamune, Shintaro Nagashima, Aya Sugiyama, Yuichiro Matsuura, Junko Tanaka
    Journal of Gastroenterology and Hepatology.2018; 33(4): 855.     CrossRef
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    Natalia V. Yunusova, Irina V. Kondakova, Larisa A. Kolomiets, Sergey G. Afanas’ev, Anastasia Yu. Kishkina, Liudmila V. Spirina
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2018; 12(5): 807.     CrossRef
  • Specific features of colorectal cancer in patients with metabolic syndrome: a matched case-control analysis of 772 patients
    Alban Zarzavadjian Le Bian, Christine Denet, Nicolas Tabchouri, Gianfranco Donatelli, Philippe Wind, Christophe Louvet, Mostefa Bennamoun, Christos Christidis, Thierry Perniceni, David Fuks, Brice Gayet
    Langenbeck's Archives of Surgery.2018; 403(4): 443.     CrossRef
  • Effect of Work-Related Sedentary Time on Overall Health Profile in Active vs. Inactive Office Workers
    Pauline M. Genin, Pascal Dessenne, Julien Finaud, Bruno Pereira, Frederic Dutheil, David Thivel, Martine Duclos
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    Joon Sung Kim, Byung-Wook Kim
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The Economic Burden of Cancers Attributable to Metabolic Syndrome in Korea
Dongwoo Kim, Seok-Jun Yoon, Young-Hoon Gong, Young Ae Kim, Hye-Young Seo, Jihyun Yoon, A-Rim Kim
J Prev Med Public Health. 2015;48(4):180-187.   Published online July 20, 2015
DOI: https://doi.org/10.3961/jpmph.15.022
  • 9,137 View
  • 113 Download
  • 12 Crossref
AbstractAbstract PDF
Objectives
Metabolic syndrome is an important etiologic factor in the development of certain types of cancers. The economic cost of the treatment of cancer has been steadily increasing. We therefore estimated the economic burden of cancers attributable to metabolic syndrome in Korea.
Methods
We reviewed metabolic syndrome-related cancers and relative risk and then calculated population attributable fractions. We analyzed insurance claims data for metabolic syndrome-related cancers in 2012 in order to estimate the direct costs associated with these cancers, including hospitalization, outpatient visits, transportation costs, and caregivers’ costs as well as indirect costs such as loss of productivity due to cancer treatment and premature death.
Results
In 2012, 18 070 patients in Korea had cancers attributable to metabolic syndrome. The economic burden was USD 199.8 million and the direct and indirect costs were USD 124.5 million and USD 75.3 million, respectively.
Conclusions
We estimated the economic burden of cancers attributable to metabolic syndrome in Korea and the efforts are necessary to reduce this burden.
Summary

Citations

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  • Predicting Habitual Use of Wearable Health Devices Among Middle-aged Individuals With Metabolic Syndrome Risk Factors in South Korea: Cross-sectional Study
    Jaeyoung Ha, Jungmi Park, Sangyi Lee, Jeong Lee, Jin-Young Choi, Junhyoung Kim, Sung-il Cho, Gyeong-Suk Jeon
    JMIR Formative Research.2023; 7: e42087.     CrossRef
  • Tools to assess employment readiness for colorectal cancer survivors: A scoping review
    Mingshuang Ding, Elise Gane, Harry Wiffen, Venerina Johnston
    Cancer Medicine.2023; 12(17): 18327.     CrossRef
  • Prevalence of Metabolic Syndrome and Its Association with Sociodemographic Characteristics in Participants of a Public Chronic Disease Control Program in Medellin, Colombia, in 2018


    Luis Felipe Higuita-Gutiérrez, Wilson de Jesús Martínez Quiroz, Jaiberth Antonio Cardona-Arias
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 1161.     CrossRef
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    Bing Ling, Li Zhao, Jixiu Yi
    Medicine.2020; 99(35): e21574.     CrossRef
  • The Economic Burden of Cancers Attributable to Infection in the Republic of Korea: A Prevalence-Based Study
    Thi Xuan Trinh Nguyen, Minji Han, Moran Ki, Young Ae Kim, Jin-Kyoung Oh
    International Journal of Environmental Research and Public Health.2020; 17(20): 7592.     CrossRef
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    Thi Nguyen, Minji Han, Jin-Kyoung Oh
    Tobacco Induced Diseases.2019;[Epub]     CrossRef
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    Joo Eun Lee, Chung Mo Nam, Sang Gyu Lee, Sohee Park, Tae Hyun Kim, Eun‐Cheol Park
    European Journal of Cancer Care.2019;[Epub]     CrossRef
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    Nutrients.2019; 11(8): 1755.     CrossRef
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    Minji Park, Seran Min, Yu Jin Cho, Sunwoo Kim, Hyuktae Kwon, Hee-Kyung Joh, Bumjo Oh, Seung-Won Oh, Ho Chun Choi, Cheol Min Lee
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  • The Korean Gastric Cancer Cohort Study: Study Protocol and Brief Results of a Large-Scale Prospective Cohort Study
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Economic Burden of Colorectal Cancer in Korea
Ju-Young Byun, Seok-Jun Yoon, In-Hwan Oh, Young Ae Kim, Hye-Young Seo, Yo-Han Lee
J Prev Med Public Health. 2014;47(2):84-93.   Published online March 31, 2014
DOI: https://doi.org/10.3961/jpmph.2014.47.2.84
  • 14,319 View
  • 143 Download
  • 17 Crossref
AbstractAbstract PDF
Objectives

The incidence and survival rate of colorectal cancer in Korea are increasing because of improved screening, treatment technologies, and lifestyle changes. In this aging population, increases in economic cost result. This study was conducted to estimate the economic burden of colorectal cancer utilizing claims data from the Health Insurance Review and Assessment Service.

Methods

Economic burdens of colorectal cancer were estimated using prevalence data and patients were defined as those who received ambulatory treatment from medical institutions or who had been hospitalized due to colorectal cancer under the International Classification of Disease 10th revision codes from C18-C21. The economic burdens of colorectal cancer were calculated as direct costs and indirect costs.

Results

The prevalence rate (per 100 000 people) of those who were treated for colorectal cancer during 2010 was 165.48. The economic burdens of colorectal cancer in 2010 were 3 trillion and 100 billion Korean won (KRW), respectively. Direct costs included 1 trillion and 960 billion KRW (62.85%), respectively and indirect costs were 1 trillion and 160 billion (37.15%), respectively.

Conclusions

Colorectal cancer has a large economic burden. Efforts should be made to reduce the economic burden of the disease through primary and secondary prevention.

Summary

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  • Estimating the economic burden of colorectal cancer in China, 2019–2030: A population‐level prevalence‐based analysis
    Hong Wang, Yan‐Jie Li, Lin Lei, Cheng‐Cheng Liu, Wan‐Qing Chen, Min Dai, Xin Wang, Jie‐Bin Lew, Ju‐Fang Shi, Ni Li, Jie He
    Cancer Medicine.2024;[Epub]     CrossRef
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    Bander Balkhi, Ahmed Alghamdi, Saeed Alqahtani, Marwan Al Najjar, Abdullah Al Harbi, Thamer Bin Traiki
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    Ria Garg, Vicki Cheng, Ursula Ellis, Vanay Verma, Helen McTaggart-Cowan, Stuart Peacock, Jonathan M. Loree, Mohsen Sadatsafavi, Mary A. De Vera
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    Binh Thang Tran, Kui Son Choi, Thanh Xuan Nguyen, Dae Kyung Sohn, Sun-Young Kim, Jae Kyung Suh, Van Sang Phan, Huu Tri Pham, Minh Hanh Nguyen, Thanh Binh Nguyen, Huu Khoi Hoang, Thi Thanh Binh Nguyen, Minh Tu Nguyen, Jin-Kyoung Oh
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The Economic Burden of Epilepsy in Korea, 2010
Jaehun Jung, Hye-Young Seo, Young Ae Kim, In-Hwan Oh, Yo Han Lee, Seok-Jun Yoon
J Prev Med Public Health. 2013;46(6):293-299.   Published online November 28, 2013
DOI: https://doi.org/10.3961/jpmph.2013.46.6.293
  • 9,621 View
  • 126 Download
  • 10 Crossref
AbstractAbstract PDF
Objectives

The purposes of this study were to evaluate the prevalence of epilepsy and to estimate the cost of epilepsy in Korea, 2010.

Methods

This study used a prevalence based approach to calculate the cost of epilepsy. Claims data from the Korean national health insurance and data from the Korea health panel, the Korea National Statistical Office's records of causes of death, and labor statistics were used to estimate the cost of epilepsy. Patients were defined as those who were hospitalized or visited an outpatient clinic during 2010 with a diagnosis of epilepsy (International Classification of Diseases 10th revision codes G40-G41). Total costs of epilepsy included direct medical costs, direct non-medical cost and indirect costs.

Results

The annual prevalence of treated epilepsy was 228 per 100 000 population, and higher in men. The age-specific prevalence was highest for teenagers. The total economic burden of epilepsy was 536 billion Korean won (KW). Indirect cost (304 billion KW) was 1.3 times greater than direct cost (232 billion KW). By gender, the male (347 billion KW) were more burdened than the female (189 billion KW). The estimated cost in young age younger than 20 years old was 24.5% of the total burden of epilepsy.

Conclusions

A significant portion of the economic burden of epilepsy is borne by people in young age. To reduce the economic burden of epilepsy, effective prevention and treatment strategies are needed.

Summary

Citations

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    Jeyul Yang, Ji Hoon Phi
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    Freya Diederich, Hans-Helmut König, Claudia Mietzner, Christian Brettschneider
    Neurology.2018; 90(1): 28.     CrossRef
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    Changwoo Shon, Hyung-Yun Choi, Jae-Jun Shim, So-Youn Park, Kyung Suk Lee, Seok-Jun Yoon, In-Hwan Oh
    Japanese Journal of Infectious Diseases.2016; 69(1): 18.     CrossRef
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    Epilepsy & Behavior.2016; 64: 122.     CrossRef

JPMPH : Journal of Preventive Medicine and Public Health