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Korean Journal of Preventive Medicine 2001;34(4): 323-330.
Cohort Study on Age at Menopause and Mortality- Kangwha Cohort Study -.
Jae Seok Hong, Sang Wook Yi, Sun Ha Jee, Tae Yong Sohn, Heechoul Ohrr
1Department of Public Health, The Graduate School, Yonsei University, Korea.
2Department of Preventive Medicine and Public Health, College of Medicine, Yonsei University, Korea.
3Graduate School of Health Science and Management, Yonsei University, Korea.
4Department of Health Service Administration, Yuhan College, Korea.
ABSTRACT
OBJECTIVE: To examine the association between age at menopause and mortality in a population-based sample of women in Kangwha, Korea. METHODS: From the Kangwha Cohort, followed-up from 1985 to 1999, the data of the over 55 year old female group(n=3,596) was used in this study to examine the association between age at menopause and mortality. We calculated the all causes mortality risk ratio and the cancer mortality risk ratio by age at menopause grouping using the Cox Proportional Hazards Model with adjustments for age, BMI, smoking, education, chronic disease, self-rated health status, alcohol consumption and age at first birth. RESULT AND CONCLUSION: Compared to women who had menopause at 45-49 years, the all causes mortality risk ratio was 1.24 for women with menopause at less than 40 years(95% CI=1.01-1.53) and 1.05 for women with menopause at over 50 years(95% CI=0.92-1.20). Also, compared to women who had menopause at 45-49 years, the cancer mortality risk ratio was 1.53 for women with menopause at less than 40 years(95% CI=0.78-2.98) and 1.17 for women with menopause at over 50 years(95% CI=0.77-1.80).
Key words: Menopause; Mortality; Cohort studies
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