Journal of Preventive Medicine and Public Health

Systematic Reviews

Pre-exposure Prophylaxis Adherence Among Men Who Have Sex With Men: A Systematic Review and Meta-analysis: Suchitra Hudrudchai, Charin Suwanwong, Pitchada Prasittichok, Kanu Priya Mohan, Nopphadol Janeaim; J Prev Med Public Health. 2024;57(1):8-17. Published online December 12, 2023; DOI: https://doi.org/10.3961/jpmph.23.345

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Abstract Summary PDF Supplementary Material: Objectives
The effectiveness and efficiency of pre-exposure prophylaxis (PrEP) in reducing the transmission of human immunodeficiency virus (HIV) among men who have sex with men (MSM) relies on how widely it is adopted and adhered to, particularly among high-risk groups of MSM. The meta-analysis aimed to collect and analyze existing evidence on various factors related to PrEP adherence in MSM, including demographic characteristics, sexual behaviors, substance use, and psychosocial factors.
Methods
The meta-analysis followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The search included articles published between January 2018 and December 2022, obtained from the PubMed, ScienceDirect, and Scopus databases. The studies that were included in the analysis reported the proportion of MSM who demonstrated adherence to PrEP and underwent quality appraisal using the Newcastle-Ottawa Scale.
Results
Of the 268 studies initially identified, only 12 met the inclusion criteria and were included in the final meta-analysis. The findings indicated that education (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.12 to 2.40), number of sexual partners (OR, 1.16; 95% CI, 1.02 to 1.31), engaging in sexual activities with an human immunodeficiency virus-positive partner (OR, 1.59; 95% CI, 1.16 to 2.26), substance use (OR, 0.83; 95% CI, 0.70 to 0.99), and lower levels of depression (OR, 0.55; 95% CI, 0.37 to 0.82) were associated with higher rates of PrEP adherence among MSM.
Conclusions
Despite these findings, further research is necessary to investigate PrEP adherence more comprehensively. The findings of this meta-analysis can be utilized to inform interventions aimed at improving PrEP adherence among MSM and provide directions for future research in this area.; Summary

Key Message
This systematic review and meta-analysis confirmed that factors such as education, number of sexual partners, engagement in sexual activities with an HIV-positive partner, substance use, and lower levels of depression were associated with higher rates of PrEP adherence among MSM. Healthcare providers and interventions should take these aspects into consideration when developing strategies to promote optimal PrEP adherence and reduce the risk of HIV transmission.

Factors Associated With Failure of Health System Reform: A Systematic Review and Meta-synthesis: Mahboubeh Bayat, Tahereh Kashkalani, Mahmoud Khodadost, Azad Shokri, Hamed Fattahi, Faeze Ghasemi Seproo, Fatemeh Younesi, Roghayeh khalilnezhad; J Prev Med Public Health. 2023;56(2):128-144. Published online March 14, 2023; DOI: https://doi.org/10.3961/jpmph.22.394

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Objectives
The health system reform process is highly political and controversial, and in most cases, it fails to realize its intended goals. This study was conducted to synthesize factors underlying the failure of health system reforms.
Methods
In this systematic review and meta-synthesis, we searched 9 international and regional databases to identify qualitative and mixed-methods studies published up to December 2019. Using thematic synthesis, we analyzed the data. We utilized the Standards for Reporting Qualitative Research checklist for quality assessment.
Results
After application of the inclusion and exclusion criteria, 40 of 1837 articles were included in the content analysis. The identified factors were organized into 7 main themes and 32 sub-themes. The main themes included: (1) reforms initiators’ attitudes and knowledge; (2) weakness of political support; (3) lack of interest group support; (4) insufficient comprehensiveness of the reform; (5) problems related to the implementation of the reform; (6) harmful consequences of reform implementation; and (7) the political, economic, cultural, and social conditions of the society in which the reform takes place.
Conclusions
Health system reform is a deep and extensive process, and shortcomings and weaknesses in each step have overcome health reform attempts in many countries. Awareness of these failure factors and appropriate responses to these issues can help policymakers properly plan and implement future reform programs and achieve the ultimate goals of reform: to improve the quantity and quality of health services and the health of society.

Summary

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Inducing collective action intentions for healthcare reform through medical crowdfunding framing
Krystallia Moysidou, Smadar Cohen Chen
Social Science & Medicine.2023; 333: 116090. CrossRef

Challenges to Achieving Universal Health Coverage Throughout the World: A Systematic Review: Alireza Darrudi, Mohammad Hossein Ketabchi Khoonsari, Maryam Tajvar; J Prev Med Public Health. 2022;55(2):125-133. Published online March 8, 2022; DOI: https://doi.org/10.3961/jpmph.21.542

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Abstract PDF Supplementary Material

Objectives
No systematic review has explored the challenges related to worldwide universal health coverage (UHC). This study reviewed challenges on the road to UHC.
Methods
A systematic electronic search of all studies that identified the challenges of worldwide UHC was conducted, without any restrictions related to the publication date or language. A hand search and a bibliographic search were also conducted to identify which texts to include in this study. These sources and citations yielded a total of 2500 articles, only 26 of which met the inclusion criteria. Relevant data from these papers were extracted, summarized, grouped, and reported in tables.
Results
Of the 26 included studies, 7 (27%) were reviews, 6 (23%) were reports, and 13 (50%) had another type of study design. The publication dates of the included studies ranged from 2011 to 2020. Nine studies (35%) were published in 2019. Using the World Health Organization conceptual model, data on all of the challenges related to UHC in terms of the 4 functions of health systems (stewardship, creating resource, financing, and delivering services) were extracted from the included studies and reported.
Conclusions
This study provides a straightforward summary of previous studies that explored the challenges related to UHC and conducted an in-depth analysis of viable solutions.

Summary

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Impact of the COVID-19 pandemic on the services provided by the Peruvian health system: an analysis of people with chronic diseases
David Villarreal-Zegarra, Luciana Bellido-Boza, Alfonso Erazo, Max Pariona-Cárdenas, Paul Valdivia-Miranda
Scientific Reports.2024;[Epub] CrossRef
In-hospital mortality of patients with acute coronary syndrome (ACS) after implementation of national health insurance (NHI) in Indonesia
Nurul Qalby, Dian S. Arsyad, Andriany Qanitha, Maarten J. Cramer, Yolande Appelman, Dara R. Pabittei, Pieter A. Doevendans, Idar Mappangara, Akhtar Fajar Muzakkir
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The use of positive deviance approach to improve health service delivery and quality of care: a scoping review
Ayelign Mengesha Kassie, Elizabeth Eakin, Biruk Beletew Abate, Aklilu Endalamaw, Anteneh Zewdie, Eskinder Wolka, Yibeltal Assefa
BMC Health Services Research.2024;[Epub] CrossRef
Access of older people to primary health care in low and middle-income countries: A systematic scoping review
Saydeh Dableh, Kate Frazer, Diarmuid Stokes, Thilo Kroll, Dirceu Henrique Paulo Mabunda
PLOS ONE.2024; 19(4): e0298973. CrossRef
Do national health insurance schemes guarantee financial risk protection in the drive towards Universal Health Coverage in West Africa? A systematic review of observational studies
Sydney N. N. T. Odonkor, Ferdinand Koranteng, Martin Appiah-Danquah, Lorena Dini, Ama Pokuaa Fenny
PLOS Global Public Health.2023; 3(8): e0001286. CrossRef
Universal health coverage evolution, ongoing trend, and future challenge: A conceptual and historical policy review
Chhabi Lal Ranabhat, Shambhu Prasad Acharya, Chiranjivi Adhikari, Chun-Bae Kim
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Networks of care to strengthen primary healthcare in resource constrained settings
Enoch Oti Agyekum, Katherine Kalaris, Blerta Maliqi, Allisyn C Moran, Andrews Ayim, Sanam Roder-DeWan
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Nchafatso G. Obonyo, Anthony O. Etyang
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Tatiele Estefâni Schönholzer, Fabiana Costa Machado Zacharias, Gabriela Gonçalves Amaral, Luciana Aparecida Fabriz, Brener Santos Silva, Ione Carvalho Pinto
Revista Latino-Americana de Enfermagem.2023;[Epub] CrossRef
Indicadores de desempenho da Atenção Primária do Programa Previne Brasil
Tatiele Estefâni Schönholzer, Fabiana Costa Machado Zacharias, Gabriela Gonçalves Amaral, Luciana Aparecida Fabriz, Brener Santos Silva, Ione Carvalho Pinto
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Performance indicators of Primary Care of the Previne Brasil Program
Tatiele Estefâni Schönholzer, Fabiana Costa Machado Zacharias, Gabriela Gonçalves Amaral, Luciana Aparecida Fabriz, Brener Santos Silva, Ione Carvalho Pinto
Revista Latino-Americana de Enfermagem.2023;[Epub] CrossRef
How should we prioritise global surgery? A capabilities approach argument for the place of surgery within every health system
Rashi Jhunjhunwala, Sridhar Venkatapuram
BMJ Global Health.2023; 8(11): e013100. CrossRef
The leading global health challenges in the artificial intelligence era
Amal Mousa Zaidan
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Role of family factors in provision and perception of social support for older people in Iran: a cross-sectional survey
Maryam Tajvar, Emily Grundy, Astrid Fletcher, Elizabeth Allen, Badriyeh Karami
BMC Primary Care.2023;[Epub] CrossRef
La enseñanza de la Salud pública para alcanzar la cobertura universal en salud.
Luis Rodolfo Morales-Rosales
Revista Científica.2023;[Epub] CrossRef
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An Evaluation of the Philippine Healthcare System: Preparing for a Robust Public Health in the Future
Dalmacito A. Cordero
Journal of Preventive Medicine and Public Health.2022; 55(3): 310. CrossRef
The impacts of donor transitions on health systems in middle-income countries: a scoping review
Hanna E Huffstetler, Shashika Bandara, Ipchita Bharali, Kaci Kennedy Mcdade, Wenhui Mao, Felicia Guo, Jiaqi Zhang, Judy Riviere, Liza Becker, Mina Mohamadi, Rebecca L Rice, Zoe King, Zoha Waqar Farooqi, Xinqi Zhang, Gavin Yamey, Osondu Ogbuoji
Health Policy and Planning.2022; 37(9): 1188. CrossRef

A Systematic Review of Spatial and Spatio-temporal Analyses in Public Health Research in Korea: Han Geul Byun, Naae Lee, Seung-sik Hwang; J Prev Med Public Health. 2021;54(5):301-308. Published online August 26, 2021; DOI: https://doi.org/10.3961/jpmph.21.160

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Abstract Summary PDF Supplementary Material

Objectives
Despite its advantages, it is not yet common practice in Korea for researchers to investigate disease associations using spatio-temporal analyses. In this study, we aimed to review health-related epidemiological research using spatio-temporal analyses and to observe methodological trends.
Methods
Health-related studies that applied spatial or spatio-temporal methods were identified using 2 international databases (PubMed and Embase) and 4 Korean academic databases (KoreaMed, NDSL, DBpia, and RISS). Two reviewers extracted data to review the included studies. A search for relevant keywords yielded 5919 studies.
Results
Of the studies that were initially found, 150 were ultimately included based on the eligibility criteria. In terms of the research topic, 5 categories with 11 subcategories were identified: chronic diseases (n=31, 20.7%), infectious diseases (n=27, 18.0%), health-related topics (including service utilization, equity, and behavior) (n=47, 31.3%), mental health (n=15, 10.0%), and cancer (n=7, 4.7%). Compared to the period between 2000 and 2010, more studies published between 2011 and 2020 were found to use 2 or more spatial analysis techniques (35.6% of included studies), and the number of studies on mapping increased 6-fold.
Conclusions
Further spatio-temporal analysis-related studies with point data are needed to provide insights and evidence to support policy decision-making for the prevention and control of infectious and chronic diseases using advances in spatial techniques.

Summary

Korean summary
본 연구는 국내 시공간 분석을 활용한 역학연구를 체계적 문헌고찰을 통해 검토하였다. 의료이용, 형평성, 건강행동 관련 주제가 가장 많았고, 두 가지 이상의 공간분석 기법을 적용한 사례가 늘었으며, 단순 지도화를 적용한 연구가 가장 많았다. 향후 시공간 분석 결과를 이용해 질병 예방과 관리 정책에 적극적으로 활용할 필요가 있다.

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Spatio-Temporal Analysis of Leptospirosis Hotspot Areas and Its Association With Hydroclimatic Factors in Selangor, Malaysia: Protocol for an Ecological Cross-sectional Study
Muhammad Akram Ab Kadir, Rosliza Abdul Manaf, Siti Aisah Mokhtar, Luthffi Idzhar Ismail
JMIR Research Protocols.2023; 12: e43712. CrossRef
Epidemiological characteristics and spatiotemporal analysis of mumps at township level in Wuhan, China, 2005–2019
Ying Peng, Peng Wang, De-guang Kong, Wen-zhen Li, Dong-ming Wang, Li Cai, Sha Lu, Bin Yu, Bang-hua Chen, Pu-Lin Liu
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International Journal of Environmental Research and Public Health.2023; 20(13): 6277. CrossRef
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Teshager Zerihun Nigussie, Temesgen T. Zewotir, Essey Kebede Muluneh, Wei Wang
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COVID-19: Special Article

COVID-19 International Collaborative Research by the Health Insurance Review and Assessment Service Using Its Nationwide Real-world Data: Database, Outcomes, and Implications: Yeunsook Rho, Do Yeon Cho, Yejin Son, Yu Jin Lee, Ji Woo Kim, Hye Jin Lee, Seng Chan You, Rae Woong Park, Jin Yong Lee; J Prev Med Public Health. 2021;54(1):8-16. Published online January 26, 2021; DOI: https://doi.org/10.3961/jpmph.20.616

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Abstract PDF

This article aims to introduce the inception and operation of the COVID-19 International Collaborative Research Project, the world’s first coronavirus disease 2019 (COVID-19) open data project for research, along with its dataset and research method, and to discuss relevant considerations for collaborative research using nationwide real-world data (RWD). COVID-19 has spread across the world since early 2020, becoming a serious global health threat to life, safety, and social and economic activities. However, insufficient RWD from patients was available to help clinicians efficiently diagnose and treat patients with COVID-19, or to provide necessary information to the government for policy-making. Countries that saw a rapid surge of infections had to focus on leveraging medical professionals to treat patients, and the circumstances made it even more difficult to promptly use COVID-19 RWD. Against this backdrop, the Health Insurance Review and Assessment Service (HIRA) of Korea decided to open its COVID-19 RWD collected through Korea’s universal health insurance program, under the title of the COVID-19 International Collaborative Research Project. The dataset, consisting of 476 508 claim statements from 234 427 patients (7590 confirmed cases) and 18 691 318 claim statements of the same patients for the previous 3 years, was established and hosted on HIRA’s in-house server. Researchers who applied to participate in the project uploaded analysis code on the platform prepared by HIRA, and HIRA conducted the analysis and provided outcome values. As of November 2020, analyses have been completed for 129 research projects, which have been published or are in the process of being published in prestigious journals.

Summary

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Chul Young Yoon, Junhun Lee, Tae Hoon Kong, Young Joon Seo
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Ji-Woo Kim, Chungsoo Kim, Kyoung-Hoon Kim, Yujin Lee, Dong Han Yu, Jeongwon Yun, Hyeran Baek, Rae Woong Park, Seng Chan You
Scientific Data.2023;[Epub] CrossRef
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BMC Pharmacology and Toxicology.2022;[Epub] CrossRef
Decreased patient visits for ankle sprain during the COVID-19 pandemic in South Korea: A nationwide retrospective study
Youngsik Hwang, Dasom Kim, Sukhyun Ryu
Preventive Medicine Reports.2022; 26: 101728. CrossRef
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Tatiane B. Ribeiro, Fátima Roque, Fidelia Ida, Ana I. Plácido, Mai Vu, Jose J. Hernández-Muñoz, Maria Teresa Herdeiro
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Perspective

Dilemmas Within the Korean Health Insurance System: Donghwi Park, Min Cheol Chang; J Prev Med Public Health. 2020;53(4):285-288. Published online July 1, 2020; DOI: https://doi.org/10.3961/jpmph.20.074

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Abstract PDF

The health insurance system in Korea is well-established and provides benefits for the entire national population. In Korea, when patients are treated at a hospital, the hospital receives a partial payment for the treatment from the patient, and the remaining amount is provided by the health insurance service. The Health Insurance Review and Assessment Service (HIRA) assesses whether the treatment was appropriate. If HIRA deems the treatment appropriate, the doctor can receive payment from the health insurance service. However, this system has several drawbacks. In this study, we aimed to provide examples of the problems that can occur in relation to HIRA assessments in Korea through actual clinical cases.

Summary

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Emmanuel Otieno, Josephine Namyalo
Journal of Preventive Medicine and Public Health.2024; 57(1): 91. CrossRef
Effect of Income Level on Stroke Incidence and Mediated Effects of Medication Adherence in Newly Diagnosed Hypertensive Patients: A Causal Mediation Analysis Using a Nationwide Cohort Study in South Korea
Seungmin Jeong, So Yeon Kong, Seung-sik Hwang, Sung-il Cho
Journal of Health Informatics and Statistics.2022; 47(4): 268. CrossRef
Diagnosis of Duchenne Muscular Dystrophy in a Presymptomatic Infant Using Next-Generation Sequencing and Chromosomal Microarray Analysis: A Case Report
Eun-Woo Park, Ye-Jee Shim, Jung-Sook Ha, Jin-Hong Shin, Soyoung Lee, Jang-Hyuk Cho
Children.2021; 8(5): 377. CrossRef

Climate Change: Review

Research Trends in Agenda-setting for Climate Change Adaptation Policy in the Public Health Sector in Korea: Su-Mi Chae, Daeeun Kim; J Prev Med Public Health. 2020;53(1):3-14. Published online January 31, 2020; DOI: https://doi.org/10.3961/jpmph.19.326

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Abstract Summary PDF Supplementary Material

Many studies have been conducted to assess the health effects of climate change in Korea. However, there has been a lack of consideration regarding how the results of these studies can be applied to relevant policies. The current study aims to examine research trends at the agenda-setting stage and to review future ways in which health-related adaptation to climate change can be addressed within national public health policy. A systematic review of previous studies of the health effects of climate change in Korea was conducted. Many studies have evaluated the effect of ambient temperature on health. A large number of studies have examined the effects on deaths and cardio-cerebrovascular diseases, but a limitation of these studies is that it is difficult to apply their findings to climate change adaptation policy in the health sector. Many infectious disease studies were also identified, but these mainly focused on malaria. Regarding climate change-related factors other than ambient temperature, studies of the health effects of these factors (with the exception of air pollution) are limited. In Korea, it can be concluded that studies conducted as part of the agenda-setting stage are insufficient, both because studies on the health effects of climate change have not ventured beyond defining the problem and because health adaptation to climate change has not been set as an important agenda item. In the future, the sharing and development of relevant databases is necessary. In addition, the priority of agenda items should be determined as part of a government initiative.

Summary

Korean summary
이 연구는 한국에서 수행된 기후변화에 따른 건강영향 연구의 동향을 살펴봄으써, 기후변화 건강 적응이 보건 정책의 어젠다로 자리 잡기 위한 연구 방향을 검토했다. 향후 국가는 기후변화 적응을 위한 우선순위 건강 문제를 검토해야 하며, 관련된 연구의 양과 질을 확보해 국가 전략의 기초가 될 수 있도록 해야 한다.

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Heat impacts on human health in the Western Pacific Region: an umbrella review
Y.T.Eunice Lo, Emily Vosper, Julian P.T. Higgins, Guy Howard
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Ho-Jang Kwon
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Original Article

Prescription of Systemic Steroids for Acute Respiratory Infections in Korean Outpatient Settings: Overall Patterns and Effects of the Prescription Appropriateness Evaluation Policy: Taejae Kim, Young Kyung Do; J Prev Med Public Health. 2020;53(2):82-88. Published online November 18, 2019; DOI: https://doi.org/10.3961/jpmph.19.090

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Objectives
The objective of this study was to identify individual and institutional factors associated with the prescription of systemic steroids in patients with acute respiratory infections and to investigate the role of a policy measure aimed to reduce inappropriate prescriptions. Methods: We used data from the National Health Insurance Service-National Sample Cohort from 2006 to 2015 and focused on episodes of acute respiratory infection. Descriptive analysis and multiple logistic regression analysis were performed to identify individual-level and institution-level factors associated with the prescription of systemic steroids. In addition, steroid prescription rates were compared with antibiotic prescription rates to assess their serial trends in relation to Health Insurance Review and Assessment Service (HIRA) Prescription Appropriateness Evaluation policy. Results: Among a total of 9 460 552 episodes of respiratory infection, the steroid prescription rate was 6.8%. Defined daily doses/1000 persons/d of steroid increased gradually until 2009, but rose sharply since 2010. The steroid prescription rate was higher among ear, nose and throat specialties (13.0%) than other specialties, and in hospitals (8.0%) than in tertiary hospitals (3.0%) and other types of institutions. Following a prolonged reduction in the steroid prescription rate, this rate increased since the HIRA Prescription Appropriateness Evaluation dropped steroids from its list of evaluation items in 2009. Such a trend reversal was not observed for the prescription rate of antibiotics, which continue to be on the HIRA Prescription Appropriateness Evaluation list. Conclusions: Specialty and type of institution are important correlates of steroid prescriptions in cases of acute respiratory infection. Steroid prescriptions can also be influenced by policy measures, such as the HIRA Prescription Appropriateness Evaluation policy.

Summary

Korean summary
이 연구에서는 요양급여 청구자료를 기준으로 급성 상기도 감염에서 스테로이드를 처방하는 경우와 관련하여 다음과 같은 특징을 확인하였다. 첫째, 환자 특성과 기관 특성을 모두 고려하였을 때 진료과목과 기관의 종별 구분에서 감기 스테로이드 처방률은 상당한 변이를 보였다. 둘째, 약제급여적정성평가 항목에서 스테로이드가 제외된 직후 처방률이 시계열적으로 상승하였으며, 이는 처방 행태에 정책 요인이 중요한 영향을 미칠 수 있음을 뜻한다.

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Lisa Rickey, Katherine Auger, Maria T. Britto, Isabelle Rodgers, Shayna Field, Alayna Odom, Madison Lehr, Alexandria Cronin, Kathleen E. Walsh
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Medicina.2021; 57(12): 1385. CrossRef

Reviews

A Scoping Review of Components of Physician-induced Demand for Designing a Conceptual Framework: Marita Mohammadshahi, Shahrooz Yazdani, Alireza Olyaeemanesh, Ali Akbari Sari, Mehdi Yaseri, Sara Emamgholipour Sefiddashti; J Prev Med Public Health. 2019;52(2):72-81. Published online December 31, 2018; DOI: https://doi.org/10.3961/jpmph.18.238

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Abstract PDF Supplementary Material

Objectives
The current study presents a new conceptual framework for physician-induced demand that comprises several influential components and their interactions.
Methods
This framework was developed on the basis of the conceptual model proposed by Labelle. To identify the components that influenced induced demand and their interactions, a scoping review was conducted (from January 1980 to January 2017). Additionally, an expert panel was formed to formulate and expand the framework.
Results
The developed framework comprises 2 main sets of components. First, the supply side includes 9 components: physicians’ incentive for pecuniary profit or meeting their target income, physicians’ current income, the physician/population ratio, service price (tariff), payment method, consultation time, type of employment of physicians, observable characteristics of the physician, and type and size of the hospital. Second, the demand side includes 3 components: patients’ observable characteristics, patients’ non-clinical characteristics, and insurance coverage.
Conclusions
A conceptual framework that can clearly describe interactions between the components that influence induced demand is a critical step in providing a scientific basis for understanding physicians’ behavior, particularly in the field of health economics.

Summary

Citations

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High Temperatures and Kidney Disease Morbidity: A Systematic Review and Meta-analysis: Woo-Seok Lee, Woo-Sung Kim, Youn-Hee Lim, Yun-Chul Hong; J Prev Med Public Health. 2019;52(1):1-13. Published online November 20, 2018; DOI: https://doi.org/10.3961/jpmph.18.149

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Abstract Summary PDF Supplementary Material

Objectives
In recent years, serious concerns have been raised regarding the impacts of rising temperatures on health. The present study was conducted to investigate the relationship between elevated temperatures and kidney disease through a systematic review and meta-analysis.
Methods
In October 2017, 2 researchers independently searched related studies in PubMed and Embase. A meta-analysis was conducted using a random-effects model, including only studies that presented odds ratios, relative risks, or percentage changes, along with 95% confidence intervals (CIs). The characteristics of each study were summarized, and the Egger test and funnel plots were used to evaluate publication bias.
Results
Eleven studies that met the criteria were included in the final analysis. The pooled results suggest an increase of 30% (95% CI, 20 to 40) in kidney disease morbidity with high temperatures. In a disease-specific subgroup analysis, statistically significant results were observed for both renal colic or kidney stones and other renal diseases. In a study design–specific subgroup analysis, statistically significant results were observed in both time-series analyses and studies with other designs. In a temperature measure–specific subgroup analysis, significant results were likewise found for both studies using mean temperature measurements and studies measuring heat waves or heat stress.
Conclusions
Our results indicate that morbidity due to kidney disease increases at high temperatures. We also found significant results in subgroup analyses. However, further time-series analyses are needed to obtain more generalizable evidence.

Summary

Korean summary
최근들어 기온상승에 따른 건강영향과 관련하여 전 세계적으로 심각한 우려가 제기되고 있으며, 저자들은 이에 착안하여 본 연구에서 체계적 문헌고찰과 메타분석을 통해 기온상승과 신장질환 발생간의 연관성을 연구하고자 하였다. 연구결과에서는 임계온도 이상으로 기온이 상승하면 참고치에 비해 신장질환으로의 이환율이 30% (95% 신뢰구간, 20% 에서 40%) 증가함을 보였고, 부집단 분석에서도 역시 유의한 결과를 나타내었다. 그러나 보다 일반화 가능한 근거를 얻기 위해서는 기온상승과 신장질환 발생에 관한 더 많은 시계열 분석 연구가 필요할 것으로 사료된다.

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Frequency, Expected Effects, Obstacles, and Facilitators of Disclosure of Patient Safety Incidents: A Systematic Review: Minsu Ock, So Yun Lim, Min-Woo Jo, Sang-il Lee; J Prev Med Public Health. 2017;50(2):68-82. Published online January 26, 2017; DOI: https://doi.org/10.3961/jpmph.16.105

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Abstract PDF Supplementary Material

Objectives
We performed a systematic review to assess and aggregate the available evidence on the frequency, expected effects, obstacles, and facilitators of disclosure of patient safety incidents (DPSI).
Methods
We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for this systematic review and searched PubMed, Scopus, and the Cochrane Library for English articles published between 1990 and 2014. Two authors independently conducted the title screening and abstract review. Ninety-nine articles were selected for full-text reviews. One author extracted the data and another verified them.
Results
There was considerable variation in the reported frequency of DPSI among medical professionals. The main expected effects of DPSI were decreased intention of the general public to file medical lawsuits and punish medical professionals, increased credibility of medical professionals, increased intention of patients to revisit and recommend physicians or hospitals, higher ratings of quality of care, and alleviation of feelings of guilt among medical professionals. The obstacles to DPSI were fear of medical lawsuits and punishment, fear of a damaged professional reputation among colleagues and patients, diminished patient trust, the complexity of the situation, and the absence of a patient safety culture. However, the factors facilitating DPSI included the creation of a safe environment for reporting patient safety incidents, as well as guidelines and education for DPSI.
Conclusions
The reported frequency of the experience of the general public with DPSI was somewhat lower than the reported frequency of DPSI among medical professionals. Although we identified various expected effects of DPSI, more empirical evidence from real cases is required.

Summary

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Abstract PDF

Objectives
No children-specified review and meta-analysis paper about the short-term effect of fine particulate matter (PM_2.5) on hospital admissions and emergency department visits for asthma has been published. We calculated more precise pooled effect estimates on this topic and evaluated the variation in effect size according to the differences in study characteristics not considered in previous studies.
Methods
Two authors each independently searched PubMed and EMBASE for relevant studies in March, 2016. We conducted random effect meta-analyses and mixed-effect meta-regression analyses using retrieved summary effect estimates and 95% confidence intervals (CIs) and some characteristics of selected studies. The Egger’s test and funnel plot were used to check publication bias. All analyses were done using R version 3.1.3.
Results
We ultimately retrieved 26 time-series and case-crossover design studies about the short-term effect of PM_2.5 on children’s hospital admissions and emergency department visits for asthma. In the primary meta-analysis, children’s hospital admissions and emergency department visits for asthma were positively associated with a short-term 10 μg/m³ increase in PM_2.5 (relative risk, 1.048; 95% CI, 1.028 to 1.067; I²=95.7%). We also found different effect coefficients by region; the value in Asia was estimated to be lower than in North America or Europe.
Conclusions
We strengthened the evidence on the short-term effect of PM_2.5 on children’s hospital admissions and emergency department visits for asthma. Further studies from other regions outside North America and Europe regions are needed for more generalizable evidence.

Summary

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Brief Report

Citation Discovery Tools for Conducting Adaptive Meta-analyses to Update Systematic Reviews: Jong-Myon Bae, Eun Hee Kim; J Prev Med Public Health. 2016;49(2):129-133. Published online March 14, 2016; DOI: https://doi.org/10.3961/jpmph.15.074

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Abstract PDF

Objectives
The systematic review (SR) is a research methodology that aims to synthesize related evidence. Updating previously conducted SRs is necessary when new evidence has been produced, but no consensus has yet emerged on the appropriate update methodology. The authors have developed a new SR update method called ‘adaptive meta-analysis’ (AMA) using the ‘cited by’, ‘similar articles’, and ‘related articles’ citation discovery tools in the PubMed and Scopus databases. This study evaluates the usefulness of these citation discovery tools for updating SRs.
Methods
Lists were constructed by applying the citation discovery tools in the two databases to the articles analyzed by a published SR. The degree of overlap between the lists and distribution of excluded results were evaluated.
Results
The articles ultimately selected for the SR update meta-analysis were found in the lists obtained from the ‘cited by’ and ‘similar’ tools in PubMed. Most of the selected articles appeared in both the ‘cited by’ lists in Scopus and PubMed. The Scopus ‘related’ tool did not identify the appropriate articles.
Conclusions
The AMA, which involves using both citation discovery tools in PubMed, and optionally, the ‘related’ tool in Scopus, was found to be useful for updating an SR.

Summary

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Original Article

Assessing Reliability of Medical Record Reviews for the Detection of Hospital Adverse Events: Minsu Ock, Sang-il Lee, Min-Woo Jo, Jin Yong Lee, Seon-Ha Kim; J Prev Med Public Health. 2015;48(5):239-248. Published online September 11, 2015; DOI: https://doi.org/10.3961/jpmph.14.049

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Abstract PDF Supplementary Material

Objectives
The purpose of this study was to assess the inter-rater reliability and intra-rater reliability of medical record review for the detection of hospital adverse events.
Methods
We conducted two stages retrospective medical records review of a random sample of 96 patients from one acute-care general hospital. The first stage was an explicit patient record review by two nurses to detect the presence of 41 screening criteria (SC). The second stage was an implicit structured review by two physicians to identify the occurrence of adverse events from the positive cases on the SC. The inter-rater reliability of two nurses and that of two physicians were assessed. The intra-rater reliability was also evaluated by using test-retest method at approximately two weeks later.
Results
In 84.2% of the patient medical records, the nurses agreed as to the necessity for the second stage review (kappa, 0.68; 95% confidence interval [CI], 0.54 to 0.83). In 93.0% of the patient medical records screened by nurses, the physicians agreed about the absence or presence of adverse events (kappa, 0.71; 95% CI, 0.44 to 0.97). When assessing intra-rater reliability, the kappa indices of two nurses were 0.54 (95% CI, 0.31 to 0.77) and 0.67 (95% CI, 0.47 to 0.87), whereas those of two physicians were 0.87 (95% CI, 0.62 to 1.00) and 0.37 (95% CI, -0.16 to 0.89).
Conclusions
In this study, the medical record review for detecting adverse events showed intermediate to good level of inter-rater and intra-rater reliability. Well organized training program for reviewers and clearly defining SC are required to get more reliable results in the hospital adverse event study.

Summary

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Review

Alcohol as a Risk Factor for Cancer: Existing Evidence in a Global Perspective: Nina Roswall, Elisabete Weiderpass; J Prev Med Public Health. 2015;48(1):1-9. Published online January 27, 2015; DOI: https://doi.org/10.3961/jpmph.14.052

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Abstract PDF

The purpose of the present review is to give an overview of the association between alcohol intake and the risk of developing cancer. Two large-scale expert reports; the World Cancer Research Fund (WCRF)/American Institute of Cancer Research (AICR) report from 2007, including its continuous update project, and the International Agency for Research of Cancer (IARC) monograph from 2012 have extensively reviewed this association in the last decade. We summarize and compare their findings, as well as relate these to the public health impact, with a particular focus on region-specific drinking patterns and disease tendencies. Our findings show that alcohol intake is strongly linked to the risk of developing cancers of the oral cavity, pharynx, larynx, oesophagus, colorectum (in men), and female breast. The two expert reports diverge on the evidence for an association with liver cancer and colorectal cancer in women, which the IARC grades as convincing, but the WCRF/AICR as probable. Despite these discrepancies, there does, however, not seem to be any doubt, that the Population Attributable Fraction of alcohol in relation to cancer is large. As alcohol intake varies largely worldwide, so does, however, also the Population Attributable Fractions, ranging from 10% in Europe to almost 0% in countries where alcohol use is banned. Given the World Health Organization’s prediction, that alcohol intake is increasing, especially in low- and middle-income countries, and steadily high in high-income countries, the need for preventive efforts to curb the number of alcohol-related cancers seems growing, as well as the need for taking a region- and gender-specific approach in both future campaigns as well as future research. The review acknowledges the potential beneficial effects of small doses of alcohol in relation to ischaemic heart disease, but a discussion of this lies without the scope of the present study.

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